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Racemic Albuterol
Racemic Albuterol is a Beta-2 adrenergic agonist (short-acting) Small molecule drug developed by Sumitomo Pharma America, Inc.. It is currently in Phase 3 development for Acute bronchospasm relief in asthma, Acute bronchospasm relief in chronic obstructive pulmonary disease (COPD). Also known as: Ventolin Inhalation Solution.
Racemic albuterol is a beta-2 adrenergic agonist that relaxes airway smooth muscle to improve breathing.
Racemic albuterol is a beta-2 adrenergic agonist that relaxes airway smooth muscle to improve breathing. Used for Acute bronchospasm relief in asthma, Acute bronchospasm relief in chronic obstructive pulmonary disease (COPD).
At a glance
| Generic name | Racemic Albuterol |
|---|---|
| Also known as | Ventolin Inhalation Solution |
| Sponsor | Sumitomo Pharma America, Inc. |
| Drug class | Beta-2 adrenergic agonist (short-acting) |
| Target | Beta-2 adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | Phase 3 |
Mechanism of action
Albuterol binds to beta-2 adrenergic receptors on bronchial smooth muscle, activating intracellular signaling that increases cAMP levels and causes bronchodilation. The racemic mixture contains both R- and S-enantiomers; the R-enantiomer is the active form, while the S-enantiomer may contribute to airway hyperresponsiveness. It is used as a rapid-acting bronchodilator for acute relief of bronchoconstriction in asthma and COPD.
Approved indications
- Acute bronchospasm relief in asthma
- Acute bronchospasm relief in chronic obstructive pulmonary disease (COPD)
Common side effects
- Tremor
- Headache
- Nervousness
- Palpitations
- Muscle cramps
- Tachycardia
Key clinical trials
- Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED) (PHASE4)
- Randomized Controlled Trial Comparing Standard Versus Positive Pressure Nebulization in Infants With Bronchiolitis to Reduce Hospital Admissions (NA)
- Efficacy and Safety of Levalbuterol in Chronic Obstructive Pulmonary Disease (COPD) (PHASE3)
- Levalbuterol Compared to Albuterol Regarding Cardiac Side Effects and Potassium Lowering Effects. (PHASE4)
- Trough Bronchoprotection Conferred by Levosalbutamol and Racemic Salbutamol (PHASE4)
- Continuous Levalbuterol for Treatment of Status Asthmaticus in Children (PHASE4)
- A Study of Daily Dosing With Levalbuterol, Racemic Albuterol, and Placebo in Pediatric Subjects With Asthma (PHASE2)
- Peak Bronchoprotection Conferred by Levosalbutamol and Racemic Salbutamol (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Racemic Albuterol CI brief — competitive landscape report
- Racemic Albuterol updates RSS · CI watch RSS
- Sumitomo Pharma America, Inc. portfolio CI
Frequently asked questions about Racemic Albuterol
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Related
- Drug class: All Beta-2 adrenergic agonist (short-acting) drugs
- Target: All drugs targeting Beta-2 adrenergic receptor
- Manufacturer: Sumitomo Pharma America, Inc. — full pipeline
- Therapeutic area: All drugs in Respiratory
- Indication: Drugs for Acute bronchospasm relief in asthma
- Indication: Drugs for Acute bronchospasm relief in chronic obstructive pulmonary disease (COPD)
- Also known as: Ventolin Inhalation Solution
- Compare: Racemic Albuterol vs similar drugs
- Pricing: Racemic Albuterol cost, discount & access