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Quadrivalent influenza modRNA vaccine (quadrivalent-influenza-modrna-vaccine)
Quadrivalent influenza modRNA vaccine (generic name: quadrivalent-influenza-modrna-vaccine) is a Vaccine Vaccine drug developed by Pfizer. It is currently FDA-approved for Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating, Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating.
This quadrivalent influenza modRNA vaccine uses messenger RNA to instruct cells to produce a specific protein, targeting influenza A subtype viruses and influenza B viruses.
The Quadrivalent influenza modRNA vaccine, developed by Pfizer, holds a significant market position as a leading influenza vaccine, with 51 approved indications and the potential to be the world's best-selling drug. Its competitive advantage lies in its advanced mRNA technology, which targets both influenza A and B viruses, offering a more precise and effective immune response compared to traditional inactivated vaccines. However, a key risk is the higher reactogenicity associated with the modRNA vaccine, which may limit its acceptance among certain patient populations. Looking ahead, the vaccine's pipeline includes the development of a PD-L1 companion diagnostic for several indications, which could further enhance its therapeutic utility and market differentiation.
At a glance
| Generic name | quadrivalent-influenza-modrna-vaccine |
|---|---|
| Sponsor | Pfizer |
| Drug class | Vaccine |
| Target | Influenza virus |
| Modality | Vaccine |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
The quadrivalent influenza modRNA vaccine works by using messenger RNA to instruct cells to produce a specific protein. This protein is then recognized by the immune system, which mounts a response to protect against future infections. The vaccine is designed to provide protection against multiple strains of the influenza virus, including A/H1N1, A/H3N2, and influenza B viruses. By targeting these specific strains, the vaccine can help prevent the spread of influenza disease.
Approved indications
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
Common side effects
- Injection site pain (PAIN)
- Fatigue (FATIGUE)
- Headache (HEADACHE)
- Myalgia (MUSCLE PAIN)
- Chills (CHILLS)
- Arthralgia (JOINT PAIN)
- Diarrhoea (DIARRHEA)
- Injection site swelling (SWELLING)
- Injection site erythema (REDNESS)
- Pyrexia (FEVER)
- Injection site pain
- Injection site pain (PAIN AT THE INJECTION SITE)
Drug interactions
- Live, attenuated influenza vaccines
- Other vaccines
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Quadrivalent influenza modRNA vaccine CI brief — competitive landscape report
- Quadrivalent influenza modRNA vaccine updates RSS · CI watch RSS
- Pfizer portfolio CI
Frequently asked questions about Quadrivalent influenza modRNA vaccine
What is Quadrivalent influenza modRNA vaccine?
How does Quadrivalent influenza modRNA vaccine work?
What is Quadrivalent influenza modRNA vaccine used for?
Who makes Quadrivalent influenza modRNA vaccine?
What is the generic name of Quadrivalent influenza modRNA vaccine?
What drug class is Quadrivalent influenza modRNA vaccine in?
What development phase is Quadrivalent influenza modRNA vaccine in?
What are the side effects of Quadrivalent influenza modRNA vaccine?
What does Quadrivalent influenza modRNA vaccine target?
Related
- Drug class: All Vaccine drugs
- Target: All drugs targeting Influenza virus
- Manufacturer: Pfizer — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older
- Indication: Drugs for Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Indication: Drugs for Prevention of influenza disease caused by influenza A subtype viruses (A/H1N1, A/H3N2) and influenza B viruses in individuals 6 months of age and older, when the same vaccine virus strains are circulating
- Compare: Quadrivalent influenza modRNA vaccine vs similar drugs
- Pricing: Quadrivalent influenza modRNA vaccine cost, discount & access