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Q/LAIV-BFS (MEDI8662)

MedImmune LLC · Phase 3 active Biologic

Q/LAIV-BFS is a quadrivalent live attenuated influenza vaccine formulated in a pre-filled, single-dose applicator for intranasal administration.

Q/LAIV-BFS is a quadrivalent live attenuated influenza vaccine formulated in a pre-filled, single-dose applicator for intranasal administration. Used for Prevention of influenza A and B in children and adults.

At a glance

Generic nameQ/LAIV-BFS (MEDI8662)
SponsorMedImmune LLC
Drug classLive attenuated influenza vaccine (LAIV)
ModalityBiologic
Therapeutic areaImmunology / Infectious Disease
PhasePhase 3

Mechanism of action

This vaccine contains four live, temperature-sensitive attenuated influenza virus strains (two influenza A and two influenza B) that replicate in the cooler upper respiratory tract but not in the warmer lower respiratory tract, inducing mucosal and systemic immune responses. The BFS (blow-fill-seal) technology provides a pre-filled, ready-to-use single-dose device that improves convenience and reduces preparation steps compared to traditional multi-dose vials.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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