{"id":"q-laiv-bfs-medi8662","safety":{"commonSideEffects":[{"rate":null,"effect":"Nasal congestion"},{"rate":null,"effect":"Runny nose"},{"rate":null,"effect":"Sore throat"},{"rate":null,"effect":"Cough"},{"rate":null,"effect":"Fever"}]},"_chembl":{"chemblId":"CHEMBL3752326","moleculeType":"Small molecule","molecularWeight":"326.30"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This vaccine contains four live, temperature-sensitive attenuated influenza virus strains (two influenza A and two influenza B) that replicate in the cooler upper respiratory tract but not in the warmer lower respiratory tract, inducing mucosal and systemic immune responses. The BFS (blow-fill-seal) technology provides a pre-filled, ready-to-use single-dose device that improves convenience and reduces preparation steps compared to traditional multi-dose vials.","oneSentence":"Q/LAIV-BFS is a quadrivalent live attenuated influenza vaccine formulated in a pre-filled, single-dose applicator for intranasal administration.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:30:45.825Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of influenza A and B in children and adults"}]},"trialDetails":[{"nctId":"NCT00952705","phase":"PHASE3","title":"A Study to Evaluate the Immunogenicity of Quadrivalent LAIV (MEDI8662) in Adults 18 to 49 Years of Age","status":"COMPLETED","sponsor":"MedImmune LLC","startDate":"2009-08","conditions":"Healthy or Stable Underlying Chronic Medical Condition","enrollment":1800}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Q/LAIV-BFS (MEDI8662)","genericName":"Q/LAIV-BFS (MEDI8662)","companyName":"MedImmune LLC","companyId":"medimmune-llc","modality":"Biologic","firstApprovalDate":"","aiSummary":"Q/LAIV-BFS is a quadrivalent live attenuated influenza vaccine formulated in a pre-filled, single-dose applicator for intranasal administration. Used for Prevention of influenza A and B in children and adults.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}