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Pudendal Nerve Block plus anesthesia
A pudendal nerve block uses local anesthetic injection to temporarily block pain signals from the pudendal nerve, typically combined with general or regional anesthesia for surgical procedures.
A pudendal nerve block uses local anesthetic injection to temporarily block pain signals from the pudendal nerve, typically combined with general or regional anesthesia for surgical procedures. Used for Anesthesia for perineal and anorectal surgical procedures, Pain management during gynecological procedures, Anesthesia for childbirth and obstetric procedures.
At a glance
| Generic name | Pudendal Nerve Block plus anesthesia |
|---|---|
| Sponsor | University of California, Los Angeles |
| Drug class | Local anesthetic nerve block procedure |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | FDA-approved |
Mechanism of action
The pudendal nerve supplies sensory and motor innervation to the perineal region. A pudendal nerve block involves injecting local anesthetic (such as lidocaine or bupivacaine) around the pudendal nerve to interrupt pain transmission. This technique is often combined with systemic anesthesia to provide comprehensive anesthesia for perineal, anorectal, or gynecological procedures, reducing the need for higher doses of systemic anesthetics.
Approved indications
- Anesthesia for perineal and anorectal surgical procedures
- Pain management during gynecological procedures
- Anesthesia for childbirth and obstetric procedures
Common side effects
- Hematoma or bruising at injection site
- Temporary nerve injury
- Local anesthetic toxicity
- Infection at injection site
- Vascular puncture
Key clinical trials
- Anatomical Measurements of Pudendal Nerve Block in Children
- Different Transcutaneous Electrical Nerve Stimulation Modes in Pudendal Neuralgia Post-prostatectomy (NA)
- Pudendal Enhancement of Enhanced Recovery After Surgery (ERAS) for Reconstructive Surgery (PEERS) (PHASE4)
- Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia (PHASE4)
- Caudal vs. Pudendal Block in Peds GU (PHASE4)
- Evaluation of a Locoregional Anesthesia Protocol by Pudendal Block in Reconstructive Surgery Clitoral (NA)
- Preventing Catheter Related Bladder Discomfort (CRBD) With Bilateral Pudendal Nerve Block (EARLY_PHASE1)
- Pudendal Nerve Block vs Penile Nerve Block for Analgesia During Pediatric Circumcision (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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