{"id":"pudendal-nerve-block-plus-anesthesia","safety":{"commonSideEffects":[{"rate":null,"effect":"Hematoma or bruising at injection site"},{"rate":null,"effect":"Temporary nerve injury"},{"rate":null,"effect":"Local anesthetic toxicity"},{"rate":null,"effect":"Infection at injection site"},{"rate":null,"effect":"Vascular puncture"}]},"_chembl":{"chemblId":"CHEMBL4297796","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The pudendal nerve supplies sensory and motor innervation to the perineal region. A pudendal nerve block involves injecting local anesthetic (such as lidocaine or bupivacaine) around the pudendal nerve to interrupt pain transmission. This technique is often combined with systemic anesthesia to provide comprehensive anesthesia for perineal, anorectal, or gynecological procedures, reducing the need for higher doses of systemic anesthetics.","oneSentence":"A pudendal nerve block uses local anesthetic injection to temporarily block pain signals from the pudendal nerve, typically combined with general or regional anesthesia for surgical procedures.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:03:20.368Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anesthesia for perineal and anorectal surgical procedures"},{"name":"Pain management during gynecological procedures"},{"name":"Anesthesia for childbirth and obstetric procedures"}]},"trialDetails":[{"nctId":"NCT07348029","phase":"","title":"Anatomical Measurements of Pudendal Nerve Block in Children","status":"NOT_YET_RECRUITING","sponsor":"Istanbul University - Cerrahpasa","startDate":"2026-01-20","conditions":"Postoperative Pain Management, Penile Surgery-Related Pain","enrollment":50},{"nctId":"NCT07348952","phase":"NA","title":"Different Transcutaneous Electrical Nerve Stimulation Modes in Pudendal Neuralgia Post-prostatectomy","status":"COMPLETED","sponsor":"Cairo University","startDate":"2023-09-01","conditions":"Transcutaneous Electrical Nerve Stimulation, Pudendal Neuralgia, Post Prostatectomy","enrollment":60},{"nctId":"NCT04171050","phase":"PHASE4","title":"Pudendal Enhancement of Enhanced Recovery After Surgery (ERAS) for Reconstructive Surgery (PEERS)","status":"COMPLETED","sponsor":"University of California, Los Angeles","startDate":"2019-11-14","conditions":"Pain Management","enrollment":44},{"nctId":"NCT06644261","phase":"PHASE4","title":"Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia","status":"RECRUITING","sponsor":"University of Louisville","startDate":"2024-06-27","conditions":"Pudendal Neuralgia, Chronic Pelvic Pain Syndrome","enrollment":40},{"nctId":"NCT05708989","phase":"PHASE4","title":"Caudal vs. Pudendal Block in Peds GU","status":"WITHDRAWN","sponsor":"University Hospitals Cleveland Medical Center","startDate":"2023-03-06","conditions":"Hypospadias, Penile Torsion, Chordee","enrollment":""},{"nctId":"NCT05058248","phase":"NA","title":"Evaluation of a Locoregional Anesthesia Protocol by Pudendal Block in Reconstructive Surgery Clitoral","status":"UNKNOWN","sponsor":"Raincy Montfermeil Hospital Group","startDate":"2021-10-14","conditions":"Reduction in Pain Within 24 Hours of Surgery","enrollment":78},{"nctId":"NCT05022160","phase":"EARLY_PHASE1","title":"Preventing Catheter Related Bladder Discomfort (CRBD) With Bilateral Pudendal Nerve Block","status":"UNKNOWN","sponsor":"Armed Forces Hospital, Pakistan","startDate":"2021-08-10","conditions":"Bladder Neoplasm, Prostatic Neoplasms","enrollment":250},{"nctId":"NCT03914365","phase":"NA","title":"Pudendal Nerve Block vs Penile Nerve Block for Analgesia During Pediatric Circumcision","status":"UNKNOWN","sponsor":"CHU de Quebec-Universite Laval","startDate":"2019-07-01","conditions":"Male Circumcision, Regional Anesthesia","enrollment":300},{"nctId":"NCT00928564","phase":"NA","title":"Addition of Pudendal Blocks to Pelvic Floor Physical Therapy for the Treatment of Pelvic Floor Tension Myalgia","status":"COMPLETED","sponsor":"University of California, Irvine","startDate":"2009-04","conditions":"Pelvic Floor Muscle Spasm","enrollment":40},{"nctId":"NCT03298997","phase":"NA","title":"Ligation and Hemorrhoidopexy Technique Versus Ligation of Hemorrhoidal Arteries Using Ultrasound for Hemorrhoids","status":"COMPLETED","sponsor":"Larissa University Hospital","startDate":"2017-10-01","conditions":"Hemorrhoids","enrollment":60},{"nctId":"NCT04288349","phase":"NA","title":"IntraopeRativE Use of periNeal Block for Hemorrhoidectomy","status":"UNKNOWN","sponsor":"Russian Society of Colorectal Surgeons","startDate":"2020-02-20","conditions":"Hemorrhoidectomy, Pudendal Nerve","enrollment":100},{"nctId":"NCT04227561","phase":"NA","title":"Analgesia for Pediatric Circumcision : Comparison of the Effectiveness of Pudendal Nerve Block to Penile Nerve Block","status":"UNKNOWN","sponsor":"Centre Hospitalier Universitaire Saint Pierre","startDate":"2020-01-17","conditions":"Anesthesia, Pediatric Circumcision","enrollment":40},{"nctId":"NCT02517996","phase":"NA","title":"Use of Preemptive Pudendal Nerve Block Prior to Hydrodistention for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS)","status":"TERMINATED","sponsor":"Johns Hopkins University","startDate":"2015-02","conditions":"Interstitial Cystitis, Painful Bladder Syndrome","enrollment":18},{"nctId":"NCT01501279","phase":"NA","title":"Ultrasound Guided Pudendal Block in Transurethral Prostatectomies","status":"COMPLETED","sponsor":"Diskapi Teaching and Research Hospital","startDate":"2011-12","conditions":"Pain, Postoperative","enrollment":40},{"nctId":"NCT01927874","phase":"NA","title":"Subarachnoid or Infiltration for Hemorrhoidectomy","status":"COMPLETED","sponsor":"Federal University of São Paulo","startDate":"2013-01","conditions":"Hemorrhoid","enrollment":40},{"nctId":"NCT02496325","phase":"NA","title":"Ultrasound-guided Pudendal Nerve Block in Children: A Descriptive Study of Feasibility","status":"COMPLETED","sponsor":"University Hospital, Montpellier","startDate":"2014-09","conditions":"Pudendal Nerve Block","enrollment":196},{"nctId":"NCT00617448","phase":"NA","title":"Ligasure Versus Diathermy Haemorrhoidectomy Under Local Anesthesia","status":"COMPLETED","sponsor":"Hospital de Viladecans","startDate":"2005-05","conditions":"Hemorrhoids","enrollment":81}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Pudendal Nerve Block plus anesthesia","genericName":"Pudendal Nerve Block plus anesthesia","companyName":"University of California, Los Angeles","companyId":"university-of-california-los-angeles","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A pudendal nerve block uses local anesthetic injection to temporarily block pain signals from the pudendal nerve, typically combined with general or regional anesthesia for surgical procedures. Used for Anesthesia for perineal and anorectal surgical procedures, Pain management during gynecological procedures, Anesthesia for childbirth and obstetric procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}