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propan-2-ol
Propan-2-ol is a simple aliphatic alcohol that acts as a solvent and disinfectant by denaturing proteins and disrupting microbial cell membranes.
Propan-2-ol is a simple aliphatic alcohol that acts as a solvent and disinfectant by denaturing proteins and disrupting microbial cell membranes. Used for Topical antisepsis and disinfection of skin, Surface disinfection.
At a glance
| Generic name | propan-2-ol |
|---|---|
| Also known as | alcohol reference |
| Sponsor | The Hong Kong Polytechnic University |
| Drug class | Topical antiseptic/disinfectant |
| Modality | Small molecule |
| Therapeutic area | Antiseptic/Disinfectant |
| Phase | FDA-approved |
Mechanism of action
Propan-2-ol (isopropyl alcohol) exerts antimicrobial effects through rapid penetration of bacterial and viral cell membranes, causing protein denaturation and cell lysis. It is commonly used as a topical antiseptic and disinfectant rather than as a systemic pharmaceutical agent. Its mechanism is non-selective and relies on general chemical disruption of microbial structures.
Approved indications
- Topical antisepsis and disinfection of skin
- Surface disinfection
Common side effects
- Skin irritation
- Drying of skin
- Contact dermatitis
Key clinical trials
- CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee (NA)
- Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process (NA)
- Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation (PHASE2)
- HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions (NA)
- Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation (PHASE2)
- Effect of Ice Pack and Warm Gel Pad Use During Drain Removal on Anxiety, Comfort, Physiological Parameters, and Patient Satisfaction Undergoing Open Urological Surgery (NA)
- Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain (NA)
- VCOM Pain Free Research Collaborative (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- propan-2-ol CI brief — competitive landscape report
- propan-2-ol updates RSS · CI watch RSS
- The Hong Kong Polytechnic University portfolio CI