{"id":"propan-2-ol","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation"},{"rate":null,"effect":"Drying of skin"},{"rate":null,"effect":"Contact dermatitis"}]},"_chembl":{"chemblId":"CHEMBL14687","moleculeType":"Small molecule","molecularWeight":"60.10"},"_dailymed":{"setId":"af9c8daa-24e8-df28-e053-2995a90a4e57","title":"LARAMED ANTIBACTERIAL HAND SANITIZER GEL (ETHYL ALCOHOL, PROPAN-2-OL) GEL [LARA KOZMETIK HIJYENIK URUNLERI SANAYI VE DIS TICARET ANONIM SIRKETI]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Propan-2-ol (isopropyl alcohol) exerts antimicrobial effects through rapid penetration of bacterial and viral cell membranes, causing protein denaturation and cell lysis. It is commonly used as a topical antiseptic and disinfectant rather than as a systemic pharmaceutical agent. Its mechanism is non-selective and relies on general chemical disruption of microbial structures.","oneSentence":"Propan-2-ol is a simple aliphatic alcohol that acts as a solvent and disinfectant by denaturing proteins and disrupting microbial cell membranes.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T02:06:20.043Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Topical antisepsis and disinfection of skin"},{"name":"Surface disinfection"}]},"trialDetails":[{"nctId":"NCT05828810","phase":"NA","title":"CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee","status":"RECRUITING","sponsor":"Sunnybrook Health Sciences Centre","startDate":"2023-07-25","conditions":"Revision Total Hip Arthroplasty (RTHA), Revision Total Knee Arthroplasty","enrollment":400},{"nctId":"NCT06967129","phase":"NA","title":"Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process","status":"COMPLETED","sponsor":"Johnson & Johnson Vision Care, Inc.","startDate":"2025-04-25","conditions":"Astigmatism","enrollment":281},{"nctId":"NCT03728335","phase":"PHASE2","title":"Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation","status":"RECRUITING","sponsor":"City of Hope Medical Center","startDate":"2019-07-11","conditions":"Acute Myeloid Leukemia","enrollment":35},{"nctId":"NCT05497583","phase":"NA","title":"HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions","status":"COMPLETED","sponsor":"Cairo University","startDate":"2023-01-15","conditions":"Universal Adhesive","enrollment":28},{"nctId":"NCT03683433","phase":"PHASE2","title":"Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation","status":"RECRUITING","sponsor":"M.D. Anderson Cancer Center","startDate":"2018-09-18","conditions":"Acute Bilineal Leukemia, Acute Biphenotypic Leukemia, Chronic Myelomonocytic Leukemia","enrollment":50},{"nctId":"NCT07408921","phase":"NA","title":"Effect of Ice Pack and Warm Gel Pad Use During Drain Removal on Anxiety, Comfort, Physiological Parameters, and Patient Satisfaction Undergoing Open Urological Surgery","status":"RECRUITING","sponsor":"Tarsus University","startDate":"2026-02-15","conditions":"Drain","enrollment":120},{"nctId":"NCT03885791","phase":"NA","title":"Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain","status":"COMPLETED","sponsor":"Washington University School of Medicine","startDate":"2019-03-22","conditions":"Pelvic Floor Myofascial Pain, Pelvic Pain, Myofascial Pain","enrollment":165},{"nctId":"NCT06533345","phase":"NA","title":"VCOM Pain Free Research Collaborative","status":"RECRUITING","sponsor":"Edward Via Virginia College of Osteopathic Medicine","startDate":"2024-08-30","conditions":"Chronic Pain","enrollment":120},{"nctId":"NCT05741164","phase":"PHASE2","title":"Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer","status":"NOT_YET_RECRUITING","sponsor":"Emory University","startDate":"2026-03-30","conditions":"Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma","enrollment":37},{"nctId":"NCT06865170","phase":"PHASE4","title":"Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?","status":"NOT_YET_RECRUITING","sponsor":"University of California, Davis","startDate":"2026-05","conditions":"Osteoarthritis (OA) of the Knee, Fear of Needles","enrollment":88},{"nctId":"NCT04203316","phase":"PHASE2","title":"Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation","status":"ACTIVE_NOT_RECRUITING","sponsor":"Children's Oncology Group","startDate":"2023-08-14","conditions":"Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia","enrollment":1},{"nctId":"NCT05920122","phase":"PHASE4","title":"Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections","status":"COMPLETED","sponsor":"Hyagriv Simhan","startDate":"2023-10-09","conditions":"Surgical Site Infection, Cesarean Section; 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