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Premixed Bioceramic material
Premixed bioceramic material provides a biocompatible scaffold that promotes bone regeneration and integration through osteoconductive and potentially osteoinductive properties.
Premixed bioceramic material provides a biocompatible scaffold that promotes bone regeneration and integration through osteoconductive and potentially osteoinductive properties. Used for Bone defect filling and regeneration in orthopedic and dental applications, Periodontal bone loss treatment.
At a glance
| Generic name | Premixed Bioceramic material |
|---|---|
| Sponsor | Ain Shams University |
| Drug class | Bone graft substitute / Bioceramic material |
| Modality | Small molecule |
| Therapeutic area | Orthopedics / Bone regeneration |
| Phase | Phase 3 |
Mechanism of action
Bioceramic materials are composed of ceramic compounds (such as hydroxyapatite, tricalcium phosphate, or their combinations) that mimic the mineral phase of natural bone. When premixed in a ready-to-use formulation, these materials serve as a three-dimensional scaffold that facilitates bone cell attachment, proliferation, and differentiation while gradually resorbing and being replaced by new bone tissue.
Approved indications
- Bone defect filling and regeneration in orthopedic and dental applications
- Periodontal bone loss treatment
Common side effects
- Infection at implant site
- Delayed bone healing
- Material displacement
Key clinical trials
- Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis (NA)
- A Comparison of Outcome of Pulpotomy on Immature Permanent Molars Between Different Calcium Silicate-based Materials : a 12 Months Clinical Study (NA)
- Clinical Efficacy of AH Plus Bioceramic Sealer (NA)
- Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy (NA)
- Clinical and Radiographic Evaluation of Three Biomimetic Materials in Pulp Therapy of Immature Young Permanent Teeth "A Randomized Controlled Clinical Trial" (PHASE3)
- Evaluation of Guided Endodontic Microsurgery and Two Different Retrograde Filling Materials (NA)
- Clinical and Radiographic Evaluation of Vital Pulpotomy Techniques in Primary Molars Using of Premixed Bioactive Bioceramic MTA (Neo-putty) as a Novel Pulpotomy Medication Versus Formocresol (NA)
- Comparative Evaluation of Three Pulpotomy Agents for Permanent Mature Molars With Irreversible Pulpitis (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Premixed Bioceramic material CI brief — competitive landscape report
- Premixed Bioceramic material updates RSS · CI watch RSS
- Ain Shams University portfolio CI