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pramocaine
pramocaine is a drug. It is currently in unknown development for Allergic otitis externa, Arthropod bite wound, Burn injury.
Pramocaine is a small molecule with a modality of a topical anesthetic and antipruritic. It has been studied for various conditions including pruritis, focal seizure, muscle soreness, ichthyosis, and pruritus, and has been used as a treatment for uremic itch in adult hemodialysis patients.
At a glance
| Generic name | pramocaine |
|---|---|
| Target | Sigma non-opioid intracellular receptor 1, Sodium channel alpha subunits; brain (Types I, II, III), Membrane-associated progesterone receptor component 1 |
| Therapeutic area | Infectious Disease |
| Phase | unknown |
Approved indications
- Allergic otitis externa
- Arthropod bite wound
- Burn injury
- Dry skin
- Eruption of skin
- Hemorrhoids
- Inflammatory dermatosis
- Itching of ear
- Itching of skin
- Minor Bacterial Skin Infections
- Minor Skin Wound Pain
- Otitis externa
- Prevent Minor Bacterial Skin Infection
- Proctitis
- Pruritus ani
- Rectal pain
- Skin irritation
- Tinea corporis
- Tinea cruris
- Tinea pedis
Common side effects
Key clinical trials
- The Effects of Cannabidiol (CBD) Cream on Delayed Onset Muscle Soreness (DOMS and Performance After Exercise (NA)
- A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults With Focal Seizures (POWER1) (Phase 2)
- A Single Center, Clinical Study to Determine the Safety and Efficacy of an Avena Sativa Skincare Regimen for Therapy-Related Pruritus and Xerosis in Cancer Patients (NA)
- The Safety of Proctofoam-HC in the Third Trimester of Pregnancy (N/A)
- A Controlled Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Pruritus in Adult Hemodialysis Patients (Phase 4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- pramocaine CI brief — competitive landscape report
- pramocaine updates RSS · CI watch RSS
- portfolio CI
Frequently asked questions about pramocaine
What is pramocaine?
What is pramocaine used for?
What development phase is pramocaine in?
What does pramocaine target?
Related
- Target: All drugs targeting Sigma non-opioid intracellular receptor 1, Sodium channel alpha subunits; brain (Types I, II, III), Membrane-associated progesterone receptor component 1
- Manufacturer: — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Allergic otitis externa
- Indication: Drugs for Arthropod bite wound
- Indication: Drugs for Burn injury
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing