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PQed Typhoid Conjugate Vaccine

PT Bio Farma · Phase 3 active Biologic

PQed Typhoid Conjugate Vaccine stimulates immune response against Salmonella typhi by presenting conjugated polysaccharide antigens to the adaptive immune system.

PQed Typhoid Conjugate Vaccine stimulates immune response against Salmonella typhi by presenting conjugated polysaccharide antigens to the adaptive immune system. Used for Prevention of typhoid fever caused by Salmonella typhi.

At a glance

Generic namePQed Typhoid Conjugate Vaccine
SponsorPT Bio Farma
Drug classConjugate vaccine
TargetSalmonella typhi polysaccharide antigen
ModalityBiologic
Therapeutic areaImmunology / Infectious Disease
PhasePhase 3

Mechanism of action

This is a conjugate vaccine that links typhoid polysaccharide antigens to a protein carrier, enhancing T-cell dependent B-cell responses and generating both antibody and cellular immunity. The conjugation strategy improves immunogenicity compared to unconjugated polysaccharide vaccines, particularly in younger populations, and provides protection against typhoid fever caused by Salmonella typhi.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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