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postoperative 0.5% Ropivacaine hydrochloride
postoperative 0.5% Ropivacaine hydrochloride is a Local anesthetic (amide) Small molecule drug developed by China Medical University, China. It is currently FDA-approved for Postoperative local and regional anesthesia, Postoperative pain management. Also known as: Rectus sheath block of 0.5% Ropivacaine hydrochloride.
Ropivacaine hydrochloride is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials.
Ropivacaine hydrochloride is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials. Used for Postoperative local and regional anesthesia, Postoperative pain management.
At a glance
| Generic name | postoperative 0.5% Ropivacaine hydrochloride |
|---|---|
| Also known as | Rectus sheath block of 0.5% Ropivacaine hydrochloride |
| Sponsor | China Medical University, China |
| Drug class | Local anesthetic (amide) |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia / Pain Management |
| Phase | FDA-approved |
Mechanism of action
Ropivacaine is an amide-type local anesthetic that reversibly inhibits sodium influx through voltage-gated sodium channels in nerve fibers, thereby preventing depolarization and nerve impulse transmission. This results in local anesthesia and analgesia in the area of administration. It is commonly used for postoperative pain management via infiltration, nerve blocks, or regional anesthesia techniques.
Approved indications
- Postoperative local and regional anesthesia
- Postoperative pain management
Common side effects
- Injection site reactions (pain, erythema)
- Transient neurological symptoms
- Systemic toxicity (CNS and cardiac effects at high doses)
- Hypotension
- Bradycardia
Key clinical trials
- A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Profile of TRD303 for Postoperative Analgesia After Abdominal Surgery in China. (PHASE3)
- Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial (NA)
- CPL-01 in the Management of Postoperative Pain After Bunionectomy (PHASE3)
- The Impact of Intrapleural Block on Postoperative Pain Caused by Drainage Tubes After Thoracoscopic Surgery (NA)
- Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy (NA)
- Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty (NA)
- ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial (NA)
- Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- postoperative 0.5% Ropivacaine hydrochloride CI brief — competitive landscape report
- postoperative 0.5% Ropivacaine hydrochloride updates RSS · CI watch RSS
- China Medical University, China portfolio CI
Frequently asked questions about postoperative 0.5% Ropivacaine hydrochloride
What is postoperative 0.5% Ropivacaine hydrochloride?
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Who makes postoperative 0.5% Ropivacaine hydrochloride?
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Related
- Drug class: All Local anesthetic (amide) drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: China Medical University, China — full pipeline
- Therapeutic area: All drugs in Anesthesia / Pain Management
- Indication: Drugs for Postoperative local and regional anesthesia
- Indication: Drugs for Postoperative pain management
- Also known as: Rectus sheath block of 0.5% Ropivacaine hydrochloride
- Compare: postoperative 0.5% Ropivacaine hydrochloride vs similar drugs
- Pricing: postoperative 0.5% Ropivacaine hydrochloride cost, discount & access