Last reviewed 2026-04-23 · How we verify

Postloading after TAVI

Postloading after TAVI refers to a procedural strategy of administering antiplatelet or anticoagulant therapy following transcatheter aortic valve implantation to prevent thrombotic complications.

Postloading after TAVI refers to a procedural strategy of administering antiplatelet or anticoagulant therapy following transcatheter aortic valve implantation to prevent thrombotic complications. Used for Prevention of thrombotic complications following transcatheter aortic valve implantation (TAVI).

At a glance

Mechanism of action

This is a clinical management protocol rather than a discrete drug entity. It involves the timing and selection of antithrombotic agents (typically dual antiplatelet therapy or anticoagulation) administered after TAVI procedures to reduce stent thrombosis, valve thrombosis, and systemic embolic events. The postloading strategy aims to optimize the balance between thrombotic protection and bleeding risk in the immediate post-procedural period.

Approved indications

• Prevention of thrombotic complications following transcatheter aortic valve implantation (TAVI)

Common side effects

• Bleeding complications
• Stent thrombosis
• Valve thrombosis

Key clinical trials

• Dual AntiPlatelet Therapies for Prevention of Periinterventional Embolic Events in TAVI (PHASE3)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Postloading after TAVI CI brief — competitive landscape report
• Postloading after TAVI updates RSS · CI watch RSS
• Charite University, Berlin, Germany portfolio CI