{"id":"postloading-after-tavi","safety":{"commonSideEffects":[{"rate":null,"effect":"Bleeding complications"},{"rate":null,"effect":"Stent thrombosis"},{"rate":null,"effect":"Valve thrombosis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a clinical management protocol rather than a discrete drug entity. It involves the timing and selection of antithrombotic agents (typically dual antiplatelet therapy or anticoagulation) administered after TAVI procedures to reduce stent thrombosis, valve thrombosis, and systemic embolic events. The postloading strategy aims to optimize the balance between thrombotic protection and bleeding risk in the immediate post-procedural period.","oneSentence":"Postloading after TAVI refers to a procedural strategy of administering antiplatelet or anticoagulant therapy following transcatheter aortic valve implantation to prevent thrombotic complications.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:29:36.815Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of thrombotic complications following transcatheter aortic valve implantation (TAVI)"}]},"trialDetails":[{"nctId":"NCT03001960","phase":"PHASE3","title":"Dual AntiPlatelet Therapies for Prevention of Periinterventional Embolic Events in TAVI","status":"UNKNOWN","sponsor":"Charite University, Berlin, Germany","startDate":"2017-03","conditions":"Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement, Intracranial Embolism","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ASS, Plavix"],"phase":"phase_3","status":"active","brandName":"Postloading after TAVI","genericName":"Postloading after TAVI","companyName":"Charite University, Berlin, Germany","companyId":"charite-university-berlin-germany","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Postloading after TAVI refers to a procedural strategy of administering antiplatelet or anticoagulant therapy following transcatheter aortic valve implantation to prevent thrombotic complications. Used for Prevention of thrombotic complications following transcatheter aortic valve implantation (TAVI).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}