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Placebo slurry
Placebo slurry is a Small molecule drug developed by University of North Carolina, Chapel Hill. It is currently FDA-approved for Control agent in clinical trials. Also known as: Sucralose.
Placebo slurry produces therapeutic effects through the patient's expectation and belief in treatment, activating endogenous healing mechanisms.
Placebo slurry is an intervention used in clinical trials for various conditions, including Ulcerative Colitis, Celiac Disease, and Familial Adenomatous Polyposis. It is used as a control group in studies comparing it to other interventions, such as Fecal Microbiota Transplantation and Mesalamine Granules.
At a glance
| Generic name | Placebo slurry |
|---|---|
| Also known as | Sucralose |
| Sponsor | University of North Carolina, Chapel Hill |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Placebo effects operate via psychological and neurobiological pathways, including expectation-driven activation of endogenous neurotransmitter systems and pain modulation circuits. The slurry formulation is an inert preparation designed to be administered as a control or comparative agent in clinical research. In marketed contexts, any therapeutic benefit derives from placebo response rather than active pharmacological mechanisms.
Approved indications
- Control agent in clinical trials
Common side effects
- Nocebo effects (adverse events attributed to placebo)
Key clinical trials
- The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia (PHASE1, PHASE2)
- Immunosafe-CeD: Are Partially Hydrolysed Gluten Harmful to Celiac Disease Patients? (NA)
- Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis (PHASE4)
- An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel (NA)
- Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy (PHASE4)
- In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste (PHASE3)
- Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis (PHASE4)
- Fecal Microbiota Therapy Vs 5-aminosalicylates for Induction of Remission in Newly Diagnosed Mild-moderately Active UC (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo slurry CI brief — competitive landscape report
- Placebo slurry updates RSS · CI watch RSS
- University of North Carolina, Chapel Hill portfolio CI
Frequently asked questions about Placebo slurry
What is Placebo slurry?
How does Placebo slurry work?
What is Placebo slurry used for?
Who makes Placebo slurry?
Is Placebo slurry also known as anything else?
What development phase is Placebo slurry in?
What are the side effects of Placebo slurry?
Related
- Manufacturer: University of North Carolina, Chapel Hill — full pipeline
- Indication: Drugs for Control agent in clinical trials
- Also known as: Sucralose
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing