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Placebo pill (for varenicline)

University of California, Los Angeles · FDA-approved active Small molecule

A placebo pill contains no active pharmaceutical ingredient and produces therapeutic effects solely through the placebo effect.

A placebo pill contains no active pharmaceutical ingredient and produces therapeutic effects solely through the placebo effect. Used for Control comparator in varenicline smoking cessation clinical trials.

At a glance

Generic namePlacebo pill (for varenicline)
SponsorUniversity of California, Los Angeles
ModalitySmall molecule
Therapeutic areaSmoking Cessation
PhaseFDA-approved

Mechanism of action

Placebo pills are inert formulations used as control comparators in clinical trials to establish the efficacy of active drugs like varenicline. They rely on psychological and psychophysiological mechanisms—patient expectation, conditioning, and natural disease course—rather than direct molecular action. In this context, the placebo serves as the comparator arm in varenicline smoking cessation trials conducted at UCLA.

Approved indications

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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