Last reviewed · How we verify
placebo nasal spray
A placebo nasal spray contains no active pharmaceutical ingredient and produces therapeutic effects solely through the placebo effect.
At a glance
| Generic name | placebo nasal spray |
|---|---|
| Also known as | Placebo, Vehicle, ingredients, Placebo control, EVK-001 Placebo |
| Sponsor | Organon and Co |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Placebo products are inert formulations designed to mimic active medications in appearance and administration route. When administered as a nasal spray, they may produce symptom relief through psychological mechanisms including expectation, conditioning, and natural disease resolution. Placebos are typically used in clinical research as control comparators to establish the true efficacy of active drugs.
Approved indications
Common side effects
Key clinical trials
- Vaccine Pandemic Preparedness Through Airway Immunology Characterization (EARLY_PHASE1)
- A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) (PHASE3)
- Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps (PHASE3)
- Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia (PHASE1, PHASE2)
- The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight (NA)
- Combination Gerotherapeutic Interventions for Healthspan Improvement (PHASE3)
- A Clinical Study of Semaglutide Nasal Spray in Overweight or Obese Adults (PHASE1)
- Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD) (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- placebo nasal spray CI brief — competitive landscape report
- placebo nasal spray updates RSS · CI watch RSS
- Organon and Co portfolio CI