Last reviewed · How we verify
Placebo matching Seroquel XR
This is a placebo formulation designed to match the appearance and characteristics of Seroquel XR (quetiapine extended-release) for use as a control in clinical trials.
This is a placebo formulation designed to match the appearance and characteristics of Seroquel XR (quetiapine extended-release) for use as a control in clinical trials. Used for Clinical trial control for Seroquel XR studies.
At a glance
| Generic name | Placebo matching Seroquel XR |
|---|---|
| Sponsor | AstraZeneca |
| Modality | Small molecule |
| Therapeutic area | Psychiatry |
| Phase | FDA-approved |
Mechanism of action
Placebo matching formulations are inactive preparations manufactured to be identical or nearly identical in appearance, taste, and physical properties to the active drug being studied. In this case, it matches Seroquel XR to enable blinded clinical trial designs where neither patients nor researchers know who receives active quetiapine or placebo, ensuring unbiased assessment of drug efficacy and safety.
Approved indications
- Clinical trial control for Seroquel XR studies
Common side effects
Key clinical trials
- Quetiapine for Bipolar Disorder and Alcohol Dependence (PHASE4)
- Study to Evaluate the Effect and Safety of Quetiapine Extended Release (XR) (FK949E) in Major Depressive Disorder (PHASE2)
- A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial (PHASE3)
- Evaluate the Efficacy and Safety of Quetiapine Fumarate (SEROQUEL) Extended Release as Monotherapy in the Treatment of Patients With Bipolar Depression (PHASE3)
- A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients (PHASE4)
- Quetiapine XR for Cognitive and Functional Disability in Clinically Stable Patients With Bipolar Disorder (PHASE4)
- Quetiapine for the Reduction of Cocaine Use (NA)
- Flushing in Social Anxiety Disorder on Seroquel (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo matching Seroquel XR CI brief — competitive landscape report
- Placebo matching Seroquel XR updates RSS · CI watch RSS
- AstraZeneca portfolio CI