A Double-Blind, Placebo-Controlled Trial of the Efficacy of Quetiapine for the Reduction of Cocaine Use (AZC)

NCT00631748 NA COMPLETED Results posted

This placebo-controlled trial will test the effectiveness of Seroquel XR™ for the treatment of cocaine dependence in non-psychotic individuals who are cocaine dependent.

Details

Lead sponsor	Seattle Institute for Biomedical and Clinical Research
Phase	NA
Status	COMPLETED
Enrolment	60
Start date	2008-02
Completion	2010-07

Conditions

• Cocaine Dependence
• Cocaine Abuse
• Cocaine Addiction
• Drug Abuse
• Substance Abuse

Interventions

• quetiapine fumarate
• Matched Placebo
• Cognitive-behavioral Therapy

Primary outcomes

• Timeline Followback Interview (TLFB) — Grams of cocaine used at end of study (12-weeks)
  The primary outcome measure was the self-report of cocaine use in the past week, as assessed with a Timeline Followback Interview (TLFB). The TLFB is a questionnaire in which the subject is asked to self-report how much cocaine was used and how much money was spent on cocaine every day for the past 1-2 weeks.

Countries

United States