Last reviewed · How we verify
pitocin
At a glance
| Generic name | pitocin |
|---|---|
| Also known as | oxytocin, Oxytocin infusion alone, IV Oxytocin |
| Sponsor | Duke University |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
Approved indications
Boxed warnings
- IMPORTANT NOTICE Elective induction of labor is defined as the initiation of labor in a pregnant individual who has no medical indications for induction. Since the available data are inadequate to evaluate the benefits-to-risks considerations, Pitocin is not indicated for elective induction of labor.
Common side effects
- Nausea
- Vomiting
- Premature ventricular contractions
- Cardiac arrhythmia
- Hypertensive episodes
- Bradycardia
Serious adverse events
- Uterine rupture
- Severe water intoxication with convulsions and coma
- Maternal death due to oxytocin-induced water intoxication
- Permanent CNS or brain damage
- Postpartum hemorrhage
- Subarachnoid hemorrhage
- Fatal afibrinogenemia
- Fetal death
- Neonatal seizures
- Anaphylactic reaction
Key clinical trials
- Combined Use of Oxytocin and Misoprostol in the Prevention of Post Partum Haemorrhage (PHASE4)
- 3-hour Versus 12-hour Double-balloon Catheter for Labor Induction: a Randomized Trial (NA)
- The Stimulation To Induce Mothers Study (PHASE4)
- Improving Safe Vaginal Deliveries for Delivering Mothers by Implementing an Intervention Package of 11 Evidence-based Practices and Robson Classification at a Semi-urban Hospital in Dhaka, Bangladesh (NA)
- Oxytocin to Treat PTSD (PHASE2)
- EVALUATİON OF THE EFFECTİVENESS OF A MODEL-BASED HYPNOBREASTFEEDİNG EDUCATİON PROGRAM GİVEN TO PRİMİPAROUS PREGNANT WOMEN (NA)
- Oxytocin Effects on Bone in Children With Autism Spectrum Disorder (PHASE2)
- Intra-Umbilical Vein Oxytocin Injection as an Adjunct to Active Management of the Third Stage of Labour (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- pitocin CI brief — competitive landscape report
- pitocin updates RSS · CI watch RSS
- Duke University portfolio CI