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Cocculin (picrotoxin)
Cocculin (generic name: picrotoxin) is a drug. It is currently in unknown development.
Picrotoxin blocks inhibitory neurotransmission by binding to the glycine receptor subunit alpha-2, leading to increased neuronal excitability.
Cocculin, also known as picrotoxin, is a small molecule modality targeting the glycine receptor subunit alpha-2. Its mechanism of action involves blocking inhibitory neurotransmission, leading to increased neuronal excitability. However, its commercial status and approved indications are unknown. Further research is needed to determine its potential therapeutic applications and safety profile. As a result, it is not currently a widely recognized or used pharmaceutical agent.
At a glance
| Generic name | picrotoxin |
|---|---|
| Target | Glycine receptor subunit alpha-2, Glycine receptor subunit alpha-1, Glycine receptor subunit beta |
| Therapeutic area | Metabolic |
| Phase | unknown |
Mechanism of action
Imagine your brain is like a city with many different neighborhoods. Glycine receptors are like the traffic lights that help control the flow of information between neighborhoods. Picrotoxin is like a traffic jam that blocks the 'stop' signals, causing the neighborhoods to become more active and talk to each other more.
Approved indications
Common side effects
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Cocculin CI brief — competitive landscape report
- Cocculin updates RSS · CI watch RSS
- portfolio CI
Frequently asked questions about Cocculin
What is Cocculin?
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What is the generic name of Cocculin?
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What does Cocculin target?
Related
- Target: All drugs targeting Glycine receptor subunit alpha-2, Glycine receptor subunit alpha-1, Glycine receptor subunit beta
- Manufacturer: — full pipeline
- Therapeutic area: All drugs in Metabolic
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing