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Physiological seawater adjustable nasal irrigator
A physiological saline nasal irrigator that mechanically cleanses and moisturizes nasal passages using adjustable-pressure delivery of isotonic seawater solution.
A physiological saline nasal irrigator that mechanically cleanses and moisturizes nasal passages using adjustable-pressure delivery of isotonic seawater solution. Used for Nasal congestion and sinus irrigation, Allergic rhinitis symptom relief, Post-nasal drip management.
At a glance
| Generic name | Physiological seawater adjustable nasal irrigator |
|---|---|
| Sponsor | China-Japan Union Hospital |
| Modality | Small molecule |
| Therapeutic area | Otolaryngology / Nasal Health |
| Phase | FDA-approved |
Mechanism of action
This device delivers sterile, physiological seawater (isotonic saline) to the nasal cavity at adjustable pressure levels to mechanically remove mucus, allergens, pathogens, and inflammatory debris. The isotonic formulation maintains osmotic balance with nasal mucosa, reducing irritation while promoting mucosal hydration and clearance. It is a non-pharmacological, mechanical intervention rather than a drug with a molecular mechanism.
Approved indications
- Nasal congestion and sinus irrigation
- Allergic rhinitis symptom relief
- Post-nasal drip management
- Nasal hygiene and mucus clearance
Common side effects
- Mild nasal irritation
- Temporary discomfort during irrigation
- Rare epistaxis if pressure too high
Key clinical trials
- Clinical Study on the Treatment of Rhinitis Sicca With Sodium Hyaluronate Adjustable Nasal Irrigator (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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