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Phosphate Enema (Kleen® Enema)

Nabiqasim Industries (Pvt) Ltd · FDA-approved active Small molecule

Phosphate Enema (Kleen® Enema) is a Osmotic laxative enema Small molecule drug developed by Nabiqasim Industries (Pvt) Ltd. It is currently FDA-approved for Constipation and bowel evacuation, Pre-procedure bowel cleansing (colonoscopy, sigmoidoscopy). Also known as: Brand name is Kleen® Enema.

Phosphate enema works by drawing water into the colon through osmotic action, softening stool and stimulating bowel evacuation.

Phosphate enema works by drawing water into the colon through osmotic action, softening stool and stimulating bowel evacuation. Used for Constipation and bowel evacuation, Pre-procedure bowel cleansing (colonoscopy, sigmoidoscopy).

At a glance

Generic namePhosphate Enema (Kleen® Enema)
Also known asBrand name is Kleen® Enema
SponsorNabiqasim Industries (Pvt) Ltd
Drug classOsmotic laxative enema
ModalitySmall molecule
Therapeutic areaGastroenterology
PhaseFDA-approved

Mechanism of action

The sodium phosphate and dibasic sodium phosphate salts in the enema create an osmotic gradient that pulls fluid into the intestinal lumen, increasing stool bulk and water content. This mechanical distension of the colon triggers peristalsis and defecation reflex, providing rapid bowel evacuation typically within 2–15 minutes.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Phosphate Enema (Kleen® Enema)

What is Phosphate Enema (Kleen® Enema)?

Phosphate Enema (Kleen® Enema) is a Osmotic laxative enema drug developed by Nabiqasim Industries (Pvt) Ltd, indicated for Constipation and bowel evacuation, Pre-procedure bowel cleansing (colonoscopy, sigmoidoscopy).

How does Phosphate Enema (Kleen® Enema) work?

Phosphate enema works by drawing water into the colon through osmotic action, softening stool and stimulating bowel evacuation.

What is Phosphate Enema (Kleen® Enema) used for?

Phosphate Enema (Kleen® Enema) is indicated for Constipation and bowel evacuation, Pre-procedure bowel cleansing (colonoscopy, sigmoidoscopy).

Who makes Phosphate Enema (Kleen® Enema)?

Phosphate Enema (Kleen® Enema) is developed and marketed by Nabiqasim Industries (Pvt) Ltd (see full Nabiqasim Industries (Pvt) Ltd pipeline at /company/nabiqasim-industries-pvt-ltd).

Is Phosphate Enema (Kleen® Enema) also known as anything else?

Phosphate Enema (Kleen® Enema) is also known as Brand name is Kleen® Enema.

What drug class is Phosphate Enema (Kleen® Enema) in?

Phosphate Enema (Kleen® Enema) belongs to the Osmotic laxative enema class. See all Osmotic laxative enema drugs at /class/osmotic-laxative-enema.

What development phase is Phosphate Enema (Kleen® Enema) in?

Phosphate Enema (Kleen® Enema) is FDA-approved (marketed).

What are the side effects of Phosphate Enema (Kleen® Enema)?

Common side effects of Phosphate Enema (Kleen® Enema) include Abdominal cramping, Rectal irritation, Nausea, Electrolyte imbalance (with repeated use).

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