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PHGG-rich enteral nutrtiion
PHGG-rich enteral nutrition provides partially hydrolyzed guar gum (PHGG) as a prebiotic fiber to modulate gut microbiota and improve intestinal health.
PHGG-rich enteral nutrition provides partially hydrolyzed guar gum (PHGG) as a prebiotic fiber to modulate gut microbiota and improve intestinal health. Used for Nutritional support in patients requiring enteral feeding with gastrointestinal dysfunction, Improvement of bowel function and microbiota composition in hospitalized or critically ill patients.
At a glance
| Generic name | PHGG-rich enteral nutrtiion |
|---|---|
| Sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
| Drug class | Prebiotic dietary supplement / Medical food |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology / Nutrition support |
| Phase | FDA-approved |
Mechanism of action
PHGG is a soluble dietary fiber that acts as a prebiotic, selectively promoting the growth of beneficial bacteria in the colon. This fermentation produces short-chain fatty acids (particularly butyrate) that strengthen the intestinal barrier, reduce inflammation, and improve metabolic parameters. The product is administered as a specialized enteral nutrition formulation to support gastrointestinal function and overall nutritional status.
Approved indications
- Nutritional support in patients requiring enteral feeding with gastrointestinal dysfunction
- Improvement of bowel function and microbiota composition in hospitalized or critically ill patients
Common side effects
- Bloating
- Flatulence
- Abdominal discomfort
- Diarrhea
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |