{"id":"phgg-rich-enteral-nutrtiion","safety":{"commonSideEffects":[{"rate":null,"effect":"Bloating"},{"rate":null,"effect":"Flatulence"},{"rate":null,"effect":"Abdominal discomfort"},{"rate":null,"effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"PHGG is a soluble dietary fiber that acts as a prebiotic, selectively promoting the growth of beneficial bacteria in the colon. This fermentation produces short-chain fatty acids (particularly butyrate) that strengthen the intestinal barrier, reduce inflammation, and improve metabolic parameters. The product is administered as a specialized enteral nutrition formulation to support gastrointestinal function and overall nutritional status.","oneSentence":"PHGG-rich enteral nutrition provides partially hydrolyzed guar gum (PHGG) as a prebiotic fiber to modulate gut microbiota and improve intestinal health.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:41:14.449Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Nutritional support in patients requiring enteral feeding with gastrointestinal dysfunction"},{"name":"Improvement of bowel function and microbiota composition in hospitalized or critically ill patients"}]},"trialDetails":[{"nctId":"NCT05543226","phase":"PHASE4","title":"The Effect of PHGG-rich Enteral Nutrition to on the Infection in Liver Transplant Recipients: A Prospective, Double-blind, Randomized Controlled Study","status":"UNKNOWN","sponsor":"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","startDate":"2022-10-01","conditions":"Infections","enrollment":136}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"PHGG-rich enteral nutrtiion","genericName":"PHGG-rich enteral nutrtiion","companyName":"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","companyId":"sun-yat-sen-memorial-hospital-of-sun-yat-sen-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"PHGG-rich enteral nutrition provides partially hydrolyzed guar gum (PHGG) as a prebiotic fiber to modulate gut microbiota and improve intestinal health. Used for Nutritional support in patients requiring enteral feeding with gastrointestinal dysfunction, Improvement of bowel function and microbiota composition in hospitalized or critically ill patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}