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PGL4001, progestin, drug free period
PGL4001, progestin, drug free period is a Progestin / Selective Progesterone Receptor Modulator Small molecule drug developed by PregLem SA. It is currently in Phase 3 development for Hormonal contraception with scheduled menstrual cycling. Also known as: Ulipristal acetate.
PGL4001 is a selective progesterone receptor modulator that provides contraceptive and menstrual regulation effects through progestin activity with a structured drug-free period.
PGL4001 is a selective progesterone receptor modulator that provides contraceptive and menstrual regulation effects through progestin activity with a structured drug-free period. Used for Hormonal contraception with scheduled menstrual cycling.
At a glance
| Generic name | PGL4001, progestin, drug free period |
|---|---|
| Also known as | Ulipristal acetate |
| Sponsor | PregLem SA |
| Drug class | Progestin / Selective Progesterone Receptor Modulator |
| Target | Progesterone receptor |
| Modality | Small molecule |
| Therapeutic area | Contraception / Women's Health |
| Phase | Phase 3 |
Mechanism of action
PGL4001 acts as a progestin to suppress ovulation and alter endometrial conditions, preventing pregnancy. The drug-free period design allows for scheduled withdrawal bleeding, mimicking natural menstrual cycles while maintaining contraceptive efficacy. This approach combines hormonal contraception with a defined monthly cycle pattern.
Approved indications
- Hormonal contraception with scheduled menstrual cycling
Common side effects
- Headache
- Nausea
- Breast tenderness
- Irregular bleeding patterns
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PGL4001, progestin, drug free period CI brief — competitive landscape report
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- PregLem SA portfolio CI
Frequently asked questions about PGL4001, progestin, drug free period
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Related
- Drug class: All Progestin / Selective Progesterone Receptor Modulator drugs
- Target: All drugs targeting Progesterone receptor
- Manufacturer: PregLem SA — full pipeline
- Therapeutic area: All drugs in Contraception / Women's Health
- Indication: Drugs for Hormonal contraception with scheduled menstrual cycling
- Also known as: Ulipristal acetate
- Compare: PGL4001, progestin, drug free period vs similar drugs
- Pricing: PGL4001, progestin, drug free period cost, discount & access