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Periprocedural Antibiotics

Vanderbilt University Medical Center · FDA-approved active Small molecule

Periprocedural Antibiotics is a Antibiotic prophylaxis (class varies by specific agent used) Small molecule drug developed by Vanderbilt University Medical Center. It is currently FDA-approved for Surgical site infection prophylaxis in general surgery, Surgical site infection prophylaxis in orthopedic procedures, Surgical site infection prophylaxis in cardiac surgery. Also known as: trimethoprim/sulfamethoxazole.

Periprocedural antibiotics prevent surgical site infections by providing antimicrobial coverage during and immediately after medical procedures.

Periprocedural antibiotics prevent surgical site infections by providing antimicrobial coverage during and immediately after medical procedures. Used for Surgical site infection prophylaxis in general surgery, Surgical site infection prophylaxis in orthopedic procedures, Surgical site infection prophylaxis in cardiac surgery.

At a glance

Generic namePeriprocedural Antibiotics
Also known astrimethoprim/sulfamethoxazole
SponsorVanderbilt University Medical Center
Drug classAntibiotic prophylaxis (class varies by specific agent used)
ModalitySmall molecule
Therapeutic areaInfectious Disease / Surgical Prophylaxis
PhaseFDA-approved

Mechanism of action

Periprocedural antibiotics are administered before, during, or shortly after surgical or invasive procedures to achieve adequate tissue and serum concentrations at the time of incision, reducing the risk of surgical site infections (SSIs). The timing and choice of antibiotic depend on the procedure type, patient risk factors, and local resistance patterns. These are standard prophylactic measures rather than a single drug entity.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Periprocedural Antibiotics

What is Periprocedural Antibiotics?

Periprocedural Antibiotics is a Antibiotic prophylaxis (class varies by specific agent used) drug developed by Vanderbilt University Medical Center, indicated for Surgical site infection prophylaxis in general surgery, Surgical site infection prophylaxis in orthopedic procedures, Surgical site infection prophylaxis in cardiac surgery.

How does Periprocedural Antibiotics work?

Periprocedural antibiotics prevent surgical site infections by providing antimicrobial coverage during and immediately after medical procedures.

What is Periprocedural Antibiotics used for?

Periprocedural Antibiotics is indicated for Surgical site infection prophylaxis in general surgery, Surgical site infection prophylaxis in orthopedic procedures, Surgical site infection prophylaxis in cardiac surgery, Surgical site infection prophylaxis in vascular surgery.

Who makes Periprocedural Antibiotics?

Periprocedural Antibiotics is developed and marketed by Vanderbilt University Medical Center (see full Vanderbilt University Medical Center pipeline at /company/vanderbilt-university-medical-center).

Is Periprocedural Antibiotics also known as anything else?

Periprocedural Antibiotics is also known as trimethoprim/sulfamethoxazole.

What drug class is Periprocedural Antibiotics in?

Periprocedural Antibiotics belongs to the Antibiotic prophylaxis (class varies by specific agent used) class. See all Antibiotic prophylaxis (class varies by specific agent used) drugs at /class/antibiotic-prophylaxis-class-varies-by-specific-agent-used.

What development phase is Periprocedural Antibiotics in?

Periprocedural Antibiotics is FDA-approved (marketed).

What are the side effects of Periprocedural Antibiotics?

Common side effects of Periprocedural Antibiotics include Allergic reaction (rash, urticaria), Gastrointestinal disturbance (nausea, diarrhea), Anaphylaxis (with beta-lactams), Clostridioides difficile infection.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing