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Period B
Period B is a melatonin receptor agonist that helps regulate sleep-wake cycles.
Period B is a melatonin receptor agonist that helps regulate sleep-wake cycles. Used for Insomnia.
At a glance
| Generic name | Period B |
|---|---|
| Sponsor | Apnimed |
| Drug class | melatonin receptor agonist |
| Target | MT1/MT2 melatonin receptor |
| Modality | Small molecule |
| Therapeutic area | Sleep disorders |
| Phase | FDA-approved |
Mechanism of action
Period B works by activating melatonin receptors in the brain, which helps to regulate the body's natural sleep-wake cycle. This can help improve sleep quality and duration in individuals with insomnia. By targeting the melatonin receptor, Period B can help to reduce symptoms of insomnia and improve overall sleep health.
Approved indications
- Insomnia
Common side effects
- Headache
- Nausea
- Dizziness
Key clinical trials
- Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma (PHASE3)
- Pharmacokinetic and Subjective Effects of Heated Tobacco Products (NA)
- Induction of Labor by Cervical Ripening and Transcutaneous Electrical Nerve Stimulation (TENS) (NA)
- ImmunoNutrition and Colorectal Adenocarcinoma Surgery - INCAS Study (NA)
- Intracalvariosseous Plus Intravenous Antibiotics for Moderate-to-Severe Bacterial Meningitis (NA)
- Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance (PHASE4)
- Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL) (PHASE1)
- Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Period B CI brief — competitive landscape report
- Period B updates RSS · CI watch RSS
- Apnimed portfolio CI