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Perflutren lipid microsphere
Perflutren lipid microsphere is a Small molecule drug developed by Sunnybrook Health Sciences Centre. It is currently FDA-approved. Also known as: Definity, Definity®, Microbubble contrast agent, • Definity®.
Perflutren lipid microsphere is a small molecule diagnostic agent used in contrast-enhanced ultrasound imaging. It has been studied in clinical trials for various conditions, including liver disease, breast cancer, and kidney conditions.
At a glance
| Generic name | Perflutren lipid microsphere |
|---|---|
| Also known as | Definity, Definity®, Microbubble contrast agent, • Definity®, • Microbubble contrast agent |
| Sponsor | Sunnybrook Health Sciences Centre |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy (EARLY_PHASE1)
- Prediction of Neoadjuvant Chemotherapy Response Using Contrast-Enhanced Ultrasound in Patients With Locally Advanced Breast Cancer (PHASE2, PHASE3)
- Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses (PHASE1)
- Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors
- NH002-mediated Sonoporation With Chemotherapy in Advanced Pancreatic Cancer (PHASE1)
- Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension (NA)
- Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer (PHASE3)
- A Dose Ascending Study to Evaluate the Safety of NH002 as a Contrast Agent in Cardiac Echocardiography (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Perflutren lipid microsphere CI brief — competitive landscape report
- Perflutren lipid microsphere updates RSS · CI watch RSS
- Sunnybrook Health Sciences Centre portfolio CI
Frequently asked questions about Perflutren lipid microsphere
What is Perflutren lipid microsphere?
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Is Perflutren lipid microsphere also known as anything else?
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Related
- Manufacturer: Sunnybrook Health Sciences Centre — full pipeline
- Also known as: Definity, Definity®, Microbubble contrast agent, • Definity®, • Microbubble contrast agent
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing