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Peppermint sweets
Peppermint sweets provide symptomatic relief through the cooling and soothing properties of menthol, which activates TRPM8 receptors to produce a refreshing sensation in the oral cavity and throat.
Peppermint sweets provide symptomatic relief through the cooling and soothing properties of menthol, which activates TRPM8 receptors to produce a refreshing sensation in the oral cavity and throat. Used for Symptomatic relief of minor throat irritation and cough.
At a glance
| Generic name | Peppermint sweets |
|---|---|
| Also known as | Wilhelmina® |
| Sponsor | St. Antonius Hospital |
| Target | TRPM8 receptor |
| Modality | Small molecule |
| Therapeutic area | Consumer Health / Symptomatic Relief |
| Phase | Phase 3 |
Mechanism of action
Menthol, the active compound in peppermint, binds to transient receptor potential melastatin 8 (TRPM8) channels, creating a cooling sensation that can help soothe minor throat irritation and provide temporary symptomatic relief. The mechanism is primarily sensory rather than pharmacological, making peppermint sweets a consumer health product rather than a traditional pharmaceutical agent.
Approved indications
- Symptomatic relief of minor throat irritation and cough
Common side effects
- Oral irritation or burning sensation (in sensitive individuals)
- Allergic reaction to peppermint (rare)
Key clinical trials
- The Effect of Peppermint Oil Aromatherapy on Pain, Functional Capacity and Cost in Fibromyalgia Patients (NA)
- Effect of Cardamom and Peppermint Oils on Chemotherapy-Related Nausea-Vomiting and Food Intake (NA)
- Peppermint Oil for the Treatment of Irritable Bowel Syndrome or Functional Abdominal Pain in Children: the MINT Study (PHASE3)
- Aromatherapy for Improving Post-Surgical Quality of Life (NA)
- The Effect of Peppermint Oil on Nausea, Vomiting and Retching in Cancer Patients Undergoing Chemotherapy (NA)
- Gustatory Function Following Radiotherapy to the Head and Neck
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Peppermint sweets CI brief — competitive landscape report
- Peppermint sweets updates RSS · CI watch RSS
- St. Antonius Hospital portfolio CI