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Pentacel®: DTaP-IPV/Hib combined
Pentacel®: DTaP-IPV/Hib combined is a vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Protection against diphtheria, tetanus, pertussis, poliovirus, and Haemophilus influenzae type b in children, Prevention of invasive disease caused by Haemophilus influenzae type b. Also known as: Pentacel®.
Pentacel stimulates the body's immune response to produce antibodies against diphtheria, tetanus, pertussis, poliovirus, and Haemophilus influenzae type b.
Pentacel stimulates the body's immune response to produce antibodies against diphtheria, tetanus, pertussis, poliovirus, and Haemophilus influenzae type b. Used for Protection against diphtheria, tetanus, pertussis, poliovirus, and Haemophilus influenzae type b in children, Prevention of invasive disease caused by Haemophilus influenzae type b.
At a glance
| Generic name | Pentacel®: DTaP-IPV/Hib combined |
|---|---|
| Also known as | Pentacel® |
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
This is achieved through the administration of inactivated or killed pathogens, which triggers an immune response and the production of antibodies. The antibodies then provide long-term protection against future infections.
Approved indications
- Protection against diphtheria, tetanus, pertussis, poliovirus, and Haemophilus influenzae type b in children
- Prevention of invasive disease caused by Haemophilus influenzae type b
Common side effects
- Pain, redness, or swelling at the injection site
- Fever
- Irritability
Key clinical trials
- Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants (PHASE2)
- Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US (PHASE3)
- Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers (PHASE3)
- Rates of Pertussis Disease Among Persons Receiving Pentacel® or Other Pertussis Vaccines
- Database Surveillance Safety Study of PENTACEL® Vaccine
- Safety and Immune Response of Different Pediatric Combination Vaccines. (PHASE3)
- Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar® (PHASE2)
- Study of the Safety, Immunogenicity and Lot Comparability of DAPTACEL When Administered With Other Recommended Vaccine (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Pentacel®: DTaP-IPV/Hib combined CI brief — competitive landscape report
- Pentacel®: DTaP-IPV/Hib combined updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about Pentacel®: DTaP-IPV/Hib combined
What is Pentacel®: DTaP-IPV/Hib combined?
How does Pentacel®: DTaP-IPV/Hib combined work?
What is Pentacel®: DTaP-IPV/Hib combined used for?
Who makes Pentacel®: DTaP-IPV/Hib combined?
Is Pentacel®: DTaP-IPV/Hib combined also known as anything else?
What drug class is Pentacel®: DTaP-IPV/Hib combined in?
What development phase is Pentacel®: DTaP-IPV/Hib combined in?
What are the side effects of Pentacel®: DTaP-IPV/Hib combined?
Related
- Drug class: All vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Protection against diphtheria, tetanus, pertussis, poliovirus, and Haemophilus influenzae type b in children
- Indication: Drugs for Prevention of invasive disease caused by Haemophilus influenzae type b
- Also known as: Pentacel®
- Compare: Pentacel®: DTaP-IPV/Hib combined vs similar drugs
- Pricing: Pentacel®: DTaP-IPV/Hib combined cost, discount & access