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PEG-Lyte®
PEG-Lyte is an osmotic laxative that draws water into the bowel to promote bowel evacuation.
PEG-Lyte is an osmotic laxative that draws water into the bowel to promote bowel evacuation. Used for Bowel preparation prior to colonoscopy or other gastrointestinal procedures, Constipation management.
At a glance
| Generic name | PEG-Lyte® |
|---|---|
| Sponsor | The Hospital for Sick Children |
| Drug class | Osmotic laxative |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | FDA-approved |
Mechanism of action
PEG-Lyte contains polyethylene glycol (PEG) combined with electrolytes in a balanced formulation. The PEG acts as an osmotic agent that retains water in the intestinal lumen, increasing stool bulk and promoting bowel movement without significant electrolyte absorption or dehydration. It is commonly used for bowel preparation prior to colonoscopy or other gastrointestinal procedures.
Approved indications
- Bowel preparation prior to colonoscopy or other gastrointestinal procedures
- Constipation management
Common side effects
- Nausea
- Vomiting
- Abdominal bloating
- Abdominal cramping
- Diarrhea
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PEG-Lyte® CI brief — competitive landscape report
- PEG-Lyte® updates RSS · CI watch RSS
- The Hospital for Sick Children portfolio CI