{"id":"peg-lyte","safety":{"commonSideEffects":[{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Abdominal bloating"},{"rate":null,"effect":"Abdominal cramping"},{"rate":null,"effect":"Diarrhea"}]},"_chembl":{"chemblId":"CHEMBL405705","moleculeType":"Small molecule","molecularWeight":"1256.27"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"PEG-Lyte contains polyethylene glycol (PEG) combined with electrolytes in a balanced formulation. The PEG acts as an osmotic agent that retains water in the intestinal lumen, increasing stool bulk and promoting bowel movement without significant electrolyte absorption or dehydration. It is commonly used for bowel preparation prior to colonoscopy or other gastrointestinal procedures.","oneSentence":"PEG-Lyte is an osmotic laxative that draws water into the bowel to promote bowel evacuation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:41:54.860Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bowel preparation prior to colonoscopy or other gastrointestinal procedures"},{"name":"Constipation management"}]},"trialDetails":[{"nctId":"NCT00380497","phase":"PHASE4","title":"Pico-Salax Versus Poly-Ethylene Glycol for Bowel Cleanout Before Colonoscopy in Children","status":"COMPLETED","sponsor":"The Hospital for Sick Children","startDate":"2006-09","conditions":"Colonoscopy","enrollment":83}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"PEG-Lyte®","genericName":"PEG-Lyte®","companyName":"The Hospital for Sick Children","companyId":"the-hospital-for-sick-children","modality":"Small molecule","firstApprovalDate":"","aiSummary":"PEG-Lyte is an osmotic laxative that draws water into the bowel to promote bowel evacuation. Used for Bowel preparation prior to colonoscopy or other gastrointestinal procedures, Constipation management.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}