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Passiflora ; Crataegus and Salix
This herbal combination product works by promoting cardiovascular relaxation and mild sedation through the synergistic effects of passionflower's anxiolytic properties, hawthorn's cardiotonic effects, and willow's anti-inflammatory action.
This herbal combination product works by promoting cardiovascular relaxation and mild sedation through the synergistic effects of passionflower's anxiolytic properties, hawthorn's cardiotonic effects, and willow's anti-inflammatory action. Used for Anxiety and nervous tension, Cardiovascular support and mild hypertension.
At a glance
| Generic name | Passiflora ; Crataegus and Salix |
|---|---|
| Also known as | Pasalix |
| Sponsor | Marjan Industria e Comercio ltda |
| Drug class | Herbal combination / Phytotherapeutic agent |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular / Anxiolytic |
| Phase | Phase 3 |
Mechanism of action
Passiflora (passionflower) contains alkaloids and flavonoids that modulate GABAergic neurotransmission to reduce anxiety and promote relaxation. Crataegus (hawthorn) contains flavonoids and proanthocyanidins that support cardiac function and improve coronary blood flow. Salix (willow bark) provides salicin, which has anti-inflammatory and mild analgesic properties. Together, these botanicals are intended to support cardiovascular health and emotional well-being.
Approved indications
- Anxiety and nervous tension
- Cardiovascular support and mild hypertension
Common side effects
- Dizziness
- Gastrointestinal upset
- Headache
- Allergic reactions (rare)
Key clinical trials
- Association of Passiflora Incarnata L; Crataegus Oxyacantha L and Salix Alba L. on Mild and Moderate Anxiety (PHASE3)
- Efficacy and Tolerability Study to Treat Mild and Moderate Anxiety (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Passiflora ; Crataegus and Salix CI brief — competitive landscape report
- Passiflora ; Crataegus and Salix updates RSS · CI watch RSS
- Marjan Industria e Comercio ltda portfolio CI