What is Paradione used for?

Paradione is indicated for Absence seizure, Epilepsy.

What development phase is Paradione in?

Paradione is FDA-approved (marketed).

What is the generic name of Paradione?

PARAMETHADIONE is the generic (nonproprietary) name of Paradione.

Last reviewed 2026-04-20 · How we verify

Paradione (PARAMETHADIONE)

FDA-approved approved Small molecule Quality 20/100

Paradione (Paramethadione) is a small molecule drug that targets voltage-gated T-type calcium channels. It was originally developed and is currently owned by a company not specified in the provided facts. Paradione is used to treat absence seizures and epilepsy, and was FDA approved in 1949. It is off-patent and has no active Orange Book patents, meaning it is available as a generic medication. However, there are no generic manufacturers listed.

At a glance

Generic name	PARAMETHADIONE
Drug class	paramethadione
Target	Voltage-gated T-type calcium channel
Modality	Small molecule
Therapeutic area	Neuroscience
Phase	FDA-approved
First approval	1949

Approved indications

Absence seizure
Epilepsy

Common side effects

No common side effects on file.

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
FDA label	Mechanism, indications, dosing, boxed warnings, drug interactions