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oral polio vaccine + information
Oral polio vaccine stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3, providing protection against poliomyelitis infection.
Oral polio vaccine stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3, providing protection against poliomyelitis infection. Used for Prevention of poliomyelitis (polio) in infants and children, Routine immunization against poliovirus in endemic and non-endemic regions.
At a glance
| Generic name | oral polio vaccine + information |
|---|---|
| Sponsor | Bandim Health Project |
| Drug class | Live attenuated vaccine |
| Target | Poliovirus types 1, 2, and 3 |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
The vaccine contains live attenuated (weakened) poliovirus strains that replicate in the intestinal tract, triggering both mucosal and systemic immune responses. This generates neutralizing antibodies and cellular immunity against wild-type poliovirus, preventing infection and transmission. The oral route allows for intestinal immunity development, which is particularly important for blocking fecal-oral transmission.
Approved indications
- Prevention of poliomyelitis (polio) in infants and children
- Routine immunization against poliovirus in endemic and non-endemic regions
Common side effects
- Vaccine-derived poliovirus (VDPV) shedding
- Mild gastrointestinal symptoms
- Fever
- Rash
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- oral polio vaccine + information CI brief — competitive landscape report
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- Bandim Health Project portfolio CI