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Oral Polio Vaccine

International Centre for Diarrhoeal Disease Research, Bangladesh · FDA-approved active Biologic

Oral Polio Vaccine is a Live attenuated vaccine Biologic drug developed by International Centre for Diarrhoeal Disease Research, Bangladesh. It is currently FDA-approved for Prevention of poliomyelitis caused by poliovirus types 1, 2, and 3, Routine childhood immunization against polio. Also known as: Biopolio®.

Oral Polio Vaccine stimulates the immune system to produce antibodies against poliovirus by delivering live attenuated (weakened) poliovirus strains orally.

Oral Polio Vaccine stimulates the immune system to produce antibodies against poliovirus by delivering live attenuated (weakened) poliovirus strains orally. Used for Poliomyelitis prevention in infants and children, Polio outbreak response and eradication campaigns.

At a glance

Generic nameOral Polio Vaccine
Also known asBiopolio®
SponsorInternational Centre for Diarrhoeal Disease Research, Bangladesh
Drug classLive attenuated vaccine
ModalityBiologic
Therapeutic areaImmunology / Infectious Disease
PhaseFDA-approved

Mechanism of action

OPV contains three serotypes of live attenuated poliovirus that replicate in the intestinal tract, triggering both mucosal (IgA) and systemic (IgG) immune responses. This oral administration induces intestinal immunity and prevents poliovirus replication and shedding, providing protection against all three poliovirus types and contributing to herd immunity through vaccine virus shedding.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Oral Polio Vaccine

What is Oral Polio Vaccine?

Oral Polio Vaccine is a Live attenuated vaccine drug developed by International Centre for Diarrhoeal Disease Research, Bangladesh, indicated for Prevention of poliomyelitis caused by poliovirus types 1, 2, and 3, Routine childhood immunization against polio.

How does Oral Polio Vaccine work?

Oral Polio Vaccine stimulates the immune system to produce antibodies against poliovirus by delivering live attenuated (weakened) poliovirus strains orally.

What is Oral Polio Vaccine used for?

Oral Polio Vaccine is indicated for Prevention of poliomyelitis caused by poliovirus types 1, 2, and 3, Routine childhood immunization against polio.

Who makes Oral Polio Vaccine?

Oral Polio Vaccine is developed and marketed by International Centre for Diarrhoeal Disease Research, Bangladesh (see full International Centre for Diarrhoeal Disease Research, Bangladesh pipeline at /company/international-centre-for-diarrhoeal-disease-research-bangladesh).

Is Oral Polio Vaccine also known as anything else?

Oral Polio Vaccine is also known as Biopolio®.

What drug class is Oral Polio Vaccine in?

Oral Polio Vaccine belongs to the Live attenuated vaccine class. See all Live attenuated vaccine drugs at /class/live-attenuated-vaccine.

What development phase is Oral Polio Vaccine in?

Oral Polio Vaccine is FDA-approved (marketed).

What are the side effects of Oral Polio Vaccine?

Common side effects of Oral Polio Vaccine include Vaccine-derived poliovirus (VDPV) shedding, Vaccine-associated paralytic poliomyelitis (VAPP) in immunocompromised individuals, Mild gastrointestinal symptoms.

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