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Oral estazolam medication
Oral estazolam medication is a Benzodiazepine Small molecule drug developed by The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine. It is currently FDA-approved for Insomnia (short-term management of sleep initiation and maintenance).
Estazolam is a benzodiazepine that enhances the inhibitory effects of GABA at the GABA-A receptor, promoting sedation and sleep.
Estazolam is a benzodiazepine that enhances the inhibitory effects of GABA at the GABA-A receptor, promoting sedation and sleep. Used for Insomnia (short-term management of sleep initiation and maintenance).
At a glance
| Generic name | Oral estazolam medication |
|---|---|
| Sponsor | The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine |
| Drug class | Benzodiazepine |
| Target | GABA-A receptor |
| Modality | Small molecule |
| Therapeutic area | Neurology / Sleep Medicine |
| Phase | FDA-approved |
Mechanism of action
Estazolam binds to benzodiazepine receptors on GABA-A channels in the central nervous system, increasing chloride ion influx and neuronal hyperpolarization. This potentiation of GABAergic inhibition reduces neuronal excitability, leading to sedative, anxiolytic, and hypnotic effects. The drug is used primarily for short-term management of insomnia.
Approved indications
- Insomnia (short-term management of sleep initiation and maintenance)
Common side effects
- Drowsiness
- Dizziness
- Headache
- Dependence/tolerance with prolonged use
- Cognitive impairment
Key clinical trials
- Sunitinib or Cediranib for Alveolar Soft Part Sarcoma (PHASE2)
- Treatment of Chronic Insomnia According to Yin Yang Theory and Its Correlation With Circadian Rhythm (NA)
- A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia (NA)
- Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Oral estazolam medication CI brief — competitive landscape report
- Oral estazolam medication updates RSS · CI watch RSS
- The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine portfolio CI
Frequently asked questions about Oral estazolam medication
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Related
- Drug class: All Benzodiazepine drugs
- Target: All drugs targeting GABA-A receptor
- Manufacturer: The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine — full pipeline
- Therapeutic area: All drugs in Neurology / Sleep Medicine
- Indication: Drugs for Insomnia (short-term management of sleep initiation and maintenance)
- Compare: Oral estazolam medication vs similar drugs
- Pricing: Oral estazolam medication cost, discount & access