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Oral antihyperglycemics
Oral antihyperglycemics is a Oral antihyperglycemic agents (multiple classes) Small molecule drug developed by Eli Lilly and Company. It is currently in Phase 3 development for Type 2 diabetes mellitus.
Oral antihyperglycemics lower blood glucose levels through various mechanisms including insulin secretion enhancement, insulin sensitivity improvement, or glucose absorption reduction.
Oral antihyperglycemics lower blood glucose levels through various mechanisms including insulin secretion enhancement, insulin sensitivity improvement, or glucose absorption reduction. Used for Type 2 diabetes mellitus.
At a glance
| Generic name | Oral antihyperglycemics |
|---|---|
| Sponsor | Eli Lilly and Company |
| Drug class | Oral antihyperglycemic agents (multiple classes) |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | Phase 3 |
Mechanism of action
This is a broad drug class rather than a single agent, encompassing multiple mechanistic approaches to glycemic control. Eli Lilly's oral antihyperglycemic portfolio includes agents such as sulfonylureas, meglitinides, biguanides, thiazolidinediones, DPP-4 inhibitors, and SGLT2 inhibitors, each targeting different pathways in glucose homeostasis. The specific mechanism depends on the individual compound within the class.
Approved indications
- Type 2 diabetes mellitus
Common side effects
- Hypoglycemia
- Gastrointestinal disturbances
- Weight gain
- Lactic acidosis (biguanides)
Key clinical trials
- iGlarLixi CGM Study in Chinese T2D Individuals After OADs (PHASE4)
- A Study Comparing Safety and Efficacy of SHR-3167 Fixed-Dose Titration and Individualized-Dose Titration in Adults With Type 2 Diabetes Inadequately Controlled With Oral Antihyperglycemic Agents (PHASE2)
- Impact of Date Consumption on Metabolic Control and Oxidative Stress in Patients With Type 2 Diabetes (NA)
- Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy (PHASE4)
- Comparative Study Between (SGLT-2i) and (DPP-4i) in the Prevention of DIC (PHASE4)
- Oral Anti Diabetic Agents in the Hospital (PHASE4)
- Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age (EARLY_PHASE1)
- Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 Diabetes (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Oral antihyperglycemics CI brief — competitive landscape report
- Oral antihyperglycemics updates RSS · CI watch RSS
- Eli Lilly and Company portfolio CI
Frequently asked questions about Oral antihyperglycemics
What is Oral antihyperglycemics?
How does Oral antihyperglycemics work?
What is Oral antihyperglycemics used for?
Who makes Oral antihyperglycemics?
What drug class is Oral antihyperglycemics in?
What development phase is Oral antihyperglycemics in?
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Related
- Drug class: All Oral antihyperglycemic agents (multiple classes) drugs
- Manufacturer: Eli Lilly and Company — full pipeline
- Therapeutic area: All drugs in Diabetes
- Indication: Drugs for Type 2 diabetes mellitus
- Compare: Oral antihyperglycemics vs similar drugs
- Pricing: Oral antihyperglycemics cost, discount & access