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Opioid therapy
Opioid therapy involves binding to opioid receptors in the brain, spinal cord, and other areas to reduce pain perception.
Opioid therapy involves binding to opioid receptors in the brain, spinal cord, and other areas to reduce pain perception. Used for Chronic pain, Cancer pain.
At a glance
| Generic name | Opioid therapy |
|---|---|
| Also known as | Opioids |
| Sponsor | Vertanical GmbH |
| Drug class | Opioid |
| Target | Opioid receptors |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | Phase 3 |
Mechanism of action
This binding process activates the receptor, leading to a decrease in the transmission of pain signals to the brain. Opioid therapy can be effective for managing moderate to severe pain, but it carries a risk of dependence and addiction.
Approved indications
- Chronic pain
- Cancer pain
Common side effects
- Nausea
- Constipation
- Dizziness
- Vomiting
- Headache
- Somnolence
- Pruritus
- Fatigue
- Dry mouth
- Sedation
Key clinical trials
- Opioid, HIV and Immune System (PHASE4)
- Facilitating Opioid Care Connections (NA)
- Chicago Data-driven Opioid Use Disorder Screening, Engagement, Treatment and Planning System (NA)
- Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections (PHASE2)
- Management of Pain in Lumbar Arthrodesis (PHASE4)
- Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain
- Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder (NA)
- Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |