Last reviewed · How we verify
One dose of Cefo-perazone Sulbactum
One dose of Cefo-perazone Sulbactum is a Beta-lactam antibiotic with beta-lactamase inhibitor Small molecule drug developed by Asian Institute of Gastroenterology, India. It is currently in Phase 3 development for Bacterial infections (respiratory tract, urinary tract, intra-abdominal, skin and soft tissue infections), Perioperative prophylaxis in gastrointestinal surgery. Also known as: Multiple doses of Cefo-perazone Sulbactum.
Cefoperazone/sulbactam is a beta-lactam antibiotic combined with a beta-lactamase inhibitor that kills bacteria by inhibiting cell wall synthesis while protecting against enzymatic degradation.
Cefoperazone/sulbactam is a beta-lactam antibiotic combined with a beta-lactamase inhibitor that kills bacteria by inhibiting cell wall synthesis while protecting against enzymatic degradation. Used for Bacterial infections (respiratory tract, urinary tract, intra-abdominal, skin and soft tissue infections), Perioperative prophylaxis in gastrointestinal surgery.
At a glance
| Generic name | One dose of Cefo-perazone Sulbactum |
|---|---|
| Also known as | Multiple doses of Cefo-perazone Sulbactum |
| Sponsor | Asian Institute of Gastroenterology, India |
| Drug class | Beta-lactam antibiotic with beta-lactamase inhibitor |
| Target | Penicillin-binding proteins (PBPs); bacterial beta-lactamases |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
Cefoperazone is a third-generation cephalosporin that binds to penicillin-binding proteins and disrupts bacterial cell wall cross-linking, leading to cell lysis. Sulbactam is a beta-lactamase inhibitor that protects cefoperazone from degradation by bacterial beta-lactamases, extending its spectrum of activity against beta-lactamase-producing organisms. This combination is effective against a broad range of gram-positive and gram-negative bacteria.
Approved indications
- Bacterial infections (respiratory tract, urinary tract, intra-abdominal, skin and soft tissue infections)
- Perioperative prophylaxis in gastrointestinal surgery
Common side effects
- Diarrhea
- Nausea/vomiting
- Hypersensitivity reactions
- Elevated liver enzymes
- Phlebitis at injection site
Key clinical trials
- Single-Versus Multiple-dose Antimicrobial Prophylaxis for Peroral Endoscopic Myotomy in Achalasia (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- One dose of Cefo-perazone Sulbactum CI brief — competitive landscape report
- One dose of Cefo-perazone Sulbactum updates RSS · CI watch RSS
- Asian Institute of Gastroenterology, India portfolio CI
Frequently asked questions about One dose of Cefo-perazone Sulbactum
What is One dose of Cefo-perazone Sulbactum?
How does One dose of Cefo-perazone Sulbactum work?
What is One dose of Cefo-perazone Sulbactum used for?
Who makes One dose of Cefo-perazone Sulbactum?
Is One dose of Cefo-perazone Sulbactum also known as anything else?
What drug class is One dose of Cefo-perazone Sulbactum in?
What development phase is One dose of Cefo-perazone Sulbactum in?
What are the side effects of One dose of Cefo-perazone Sulbactum?
What does One dose of Cefo-perazone Sulbactum target?
Related
- Drug class: All Beta-lactam antibiotic with beta-lactamase inhibitor drugs
- Target: All drugs targeting Penicillin-binding proteins (PBPs); bacterial beta-lactamases
- Manufacturer: Asian Institute of Gastroenterology, India — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Bacterial infections (respiratory tract, urinary tract, intra-abdominal, skin and soft tissue infections)
- Indication: Drugs for Perioperative prophylaxis in gastrointestinal surgery
- Also known as: Multiple doses of Cefo-perazone Sulbactum
- Compare: One dose of Cefo-perazone Sulbactum vs similar drugs
- Pricing: One dose of Cefo-perazone Sulbactum cost, discount & access