saline infusion

University Hospital, Linkoeping · FDA-approved active Small molecule

saline infusion is a Electrolyte solution / Fluid replacement Small molecule drug developed by University Hospital, Linkoeping. It is currently FDA-approved for Fluid and electrolyte replacement in dehydration, Perioperative fluid management, Maintenance of vascular access and hemodynamic support. Also known as: saline, Saline, Normal saline solution, 0.9% sodium chloride solution.

Saline infusion replaces or maintains fluid and electrolyte balance by delivering a sterile sodium chloride solution intravenously.

Saline infusion is used to treat conditions such as vomiting, nausea, and emesis, as well as non-small cell lung cancer and nicotine dependence. The mechanism of saline infusion is unknown, but it is administered as a lactated or potassic saline injection.

At a glance

Generic name	saline infusion
Also known as	saline, Saline, Normal saline solution, 0.9% sodium chloride solution, normal saline infusion
Sponsor	University Hospital, Linkoeping
Drug class	Electrolyte solution / Fluid replacement
Modality	Small molecule
Therapeutic area	Supportive Care / General Medicine
Phase	FDA-approved

Mechanism of action

Saline infusion is a basic supportive therapy that provides isotonic fluid containing 0.9% sodium chloride to restore intravascular volume, maintain hydration, and preserve electrolyte homeostasis. It is used across multiple clinical settings to prevent or treat dehydration, support hemodynamic stability, and serve as a vehicle for other medications.

Approved indications

• Fluid and electrolyte replacement in dehydration
• Perioperative fluid management
• Maintenance of vascular access and hemodynamic support

Common side effects

• Hyperchloremic acidosis
• Fluid overload / pulmonary edema
• Hypokalemia
• Phlebitis at infusion site

Key clinical trials

• Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP): a Randomized, Controlled Trial. (NA)
• Pulse Glucocorticoid Therapy in Patients With ST-Segment Elevation Myocardial Infarction (PHASE2)
• Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies (PHASE1)
• MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) (PHASE3)
• Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis (PHASE2)
• Water Deprivation Protocol (NA)
• Normal Saline Infusion After Intravenous Thrombolysis in Stroke (PHASE3)
• Management of Pain in Lumbar Arthrodesis (PHASE4)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• saline infusion CI brief — competitive landscape report
• saline infusion updates RSS · CI watch RSS
• University Hospital, Linkoeping portfolio CI

Frequently asked questions about saline infusion

What is saline infusion?

saline infusion is a Electrolyte solution / Fluid replacement drug developed by University Hospital, Linkoeping, indicated for Fluid and electrolyte replacement in dehydration, Perioperative fluid management, Maintenance of vascular access and hemodynamic support.

How does saline infusion work?

Saline infusion replaces or maintains fluid and electrolyte balance by delivering a sterile sodium chloride solution intravenously.

What is saline infusion used for?

saline infusion is indicated for Fluid and electrolyte replacement in dehydration, Perioperative fluid management, Maintenance of vascular access and hemodynamic support.

Who makes saline infusion?

saline infusion is developed and marketed by University Hospital, Linkoeping (see full University Hospital, Linkoeping pipeline at /company/university-hospital-linkoeping).

Is saline infusion also known as anything else?

saline infusion is also known as saline, Saline, Normal saline solution, 0.9% sodium chloride solution, normal saline infusion.

What drug class is saline infusion in?

saline infusion belongs to the Electrolyte solution / Fluid replacement class. See all Electrolyte solution / Fluid replacement drugs at /class/electrolyte-solution-fluid-replacement.

What development phase is saline infusion in?

saline infusion is FDA-approved (marketed).

What are the side effects of saline infusion?

Common side effects of saline infusion include Hyperchloremic acidosis, Fluid overload / pulmonary edema, Hypokalemia, Phlebitis at infusion site.

Related

• Drug class: All Electrolyte solution / Fluid replacement drugs
• Manufacturer: University Hospital, Linkoeping — full pipeline
• Therapeutic area: All drugs in Supportive Care / General Medicine
• Indication: Drugs for Fluid and electrolyte replacement in dehydration
• Indication: Drugs for Perioperative fluid management
• Indication: Drugs for Maintenance of vascular access and hemodynamic support
• Also known as: saline, Saline, Normal saline solution, 0.9% sodium chloride solution, normal saline infusion