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Normal saline gargle
Normal saline gargle provides mechanical cleansing and osmotic effects to soothe the throat and reduce microbial load in the oral and pharyngeal cavity.
Normal saline gargle provides mechanical cleansing and osmotic effects to soothe and rinse the oral and pharyngeal mucosa. Used for Sore throat relief and oral hygiene, Post-operative throat care, Symptomatic relief of minor throat irritation.
At a glance
| Generic name | Normal saline gargle |
|---|---|
| Sponsor | Mundipharma Manufacturing Pte Ltd. |
| Drug class | Saline rinse / Oral hygiene agent |
| Modality | Small molecule |
| Therapeutic area | Otolaryngology / Oral Care |
| Phase | FDA-approved |
Mechanism of action
Normal saline (0.9% sodium chloride solution) acts as a gentle irrigant that mechanically removes debris, mucus, and microorganisms from the throat. The isotonic saline solution helps reduce inflammation and irritation by maintaining osmotic balance in mucosal tissues, while the gargling action itself provides physical cleansing of the pharyngeal region.
Approved indications
- Sore throat relief and symptomatic management
- Oral and pharyngeal hygiene
- Post-operative throat care
Common side effects
- Mild throat irritation
- Temporary discomfort during gargling
Key clinical trials
- Stingless Bee Honey Mouth Rinse on Gingivitis (EARLY_PHASE1)
- Clinical Effectiveness Of Polishing Brush Compared To Ceramic Soft Tissue Trimming Bur In Gingival Depigmentation (NA)
- Therapeutic Effect of Manuka Honey Oral Rinse in Periodontitis Patients Undergoing Hemodialysis (PHASE3)
- The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery (NA)
- SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial (PHASE2, PHASE3)
- The Efficacy of Erythropoietin Oral Gel Versus Erythropoietin Mouthwash in the Management of Recurrent Aphthous Stomatitis (PHASE4)
- Assessment of Ozone Therapy for Management of Post-Extraction Localized Alveolar Osteitis (NA)
- Analysis of the Factors Influencing the Occurrence of Peri-implant Inflammation in Patients With Oral Implant Repair and Study on the Maintenance Effect of Subgingival Sandblasting (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Normal saline gargle CI brief — competitive landscape report
- Normal saline gargle updates RSS · CI watch RSS
- Mundipharma Manufacturing Pte Ltd. portfolio CI