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No antibiotics
No antibiotics is a Non-steroidal anti-inflammatory Small molecule drug developed by Helsinki University Central Hospital. It is currently FDA-approved for Treatment of osteoarthritis, Treatment of rheumatoid arthritis.
This drug works by blocking the action of a specific enzyme.
Researchers have studied the effectiveness of photodynamic therapy, scaling and root planing, and oral antibiotics in treating various conditions, including chronic periodontitis, acute respiratory tract infections, and pneumonia. These studies have been conducted to compare the outcomes of different interventions, such as photodynamic therapy and scaling and root planing, with and without oral antibiotics.
At a glance
| Generic name | No antibiotics |
|---|---|
| Sponsor | Helsinki University Central Hospital |
| Drug class | Non-steroidal anti-inflammatory |
| Target | COX-2 |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | FDA-approved |
Mechanism of action
The drug inhibits the enzyme's activity, leading to a decrease in the production of a certain compound. This, in turn, results in a therapeutic effect.
Approved indications
- Treatment of osteoarthritis
- Treatment of rheumatoid arthritis
Common side effects
- Gastrointestinal bleeding
- Kidney damage
Key clinical trials
- Immediate Restoration of a New Implant With High Primary Stability (NA)
- Acupuncture for Colorectal sUrgery Recovery Enhancement: A Randomized Controlled Trial Evaluating Gastrointestinal Functional Recovery After Minimally Invasive Resection (NA)
- Immediate Versus Substantiated Antibiotic Therapy in Suspected Non-Severe Ventilator-Associated Pneumonia (NA)
- Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults (PHASE1)
- PMPR and Chlorhexidine on Periodontal Disease and Vascular Function (NA)
- Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients (NA)
- Effect of Intrarectal Ice Application on Pain, Anxiety, Cortisol Levels, Development of Complications, and Hospital Readmission in Transrectal Ultrasound-Guided Prostate Biopsy (NA)
- Eye-Ear Sleep Band for Sleep Quality in Coronary Care Unit (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- No antibiotics CI brief — competitive landscape report
- No antibiotics updates RSS · CI watch RSS
- Helsinki University Central Hospital portfolio CI
Frequently asked questions about No antibiotics
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Related
- Drug class: All Non-steroidal anti-inflammatory drugs
- Target: All drugs targeting COX-2
- Manufacturer: Helsinki University Central Hospital — full pipeline
- Therapeutic area: All drugs in Pain management
- Indication: Drugs for Treatment of osteoarthritis
- Indication: Drugs for Treatment of rheumatoid arthritis
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing