Last reviewed 2026-04-23 · How we verify

NETILDEX™ ophthalmic gel

NETILDEX is a combination ophthalmic gel containing netilmicin (an aminoglycoside antibiotic) and dexamethasone (a corticosteroid) that reduces bacterial infection and inflammation in the eye.

NETILDEX is a combination ophthalmic gel containing netilmicin (an aminoglycoside antibiotic) and dexamethasone (a corticosteroid) that reduces bacterial infection and inflammation in the eye. Used for Bacterial ocular infections with associated inflammation, Post-operative ocular inflammation and infection prophylaxis.

At a glance

Mechanism of action

Netilmicin works by inhibiting bacterial protein synthesis, thereby providing broad-spectrum antimicrobial coverage against gram-positive and gram-negative ocular pathogens. Dexamethasone suppresses the inflammatory response by inhibiting phospholipase A2 and reducing prostaglandin and leukotriene production, thereby decreasing ocular inflammation, edema, and discomfort associated with infection or post-operative states.

Approved indications

• Bacterial ocular infections with associated inflammation
• Post-operative ocular inflammation and infection prophylaxis

Common side effects

• Ocular irritation or discomfort
• Transient blurred vision
• Allergic conjunctivitis
• Increased intraocular pressure (with prolonged corticosteroid use)

Key clinical trials

• Clinical Study to Evaluate the Efficacy and Tolerability of an Anti-inflammatory/Antibiotic Treatment Following Ocular Cataract Extraction (PHASE3)

Primary sources

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Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• NETILDEX™ ophthalmic gel CI brief — competitive landscape report
• NETILDEX™ ophthalmic gel updates RSS · CI watch RSS
• SIFI SpA portfolio CI