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Natural saline inhalation
Natural saline inhalation delivers isotonic sodium chloride solution via aerosol to hydrate and clear respiratory secretions.
Natural saline inhalation delivers isotonic sodium chloride solution via aerosol to hydrate and clear respiratory secretions. Used for Airway secretion clearance and mucus mobilization in respiratory conditions, Supportive care for patients with excessive or thick airway secretions.
At a glance
| Generic name | Natural saline inhalation |
|---|---|
| Also known as | Inhaled saline |
| Sponsor | Shanghai Pulmonary Hospital, Shanghai, China |
| Modality | Small molecule |
| Therapeutic area | Respiratory/Pulmonology |
| Phase | FDA-approved |
Mechanism of action
Inhaled saline acts as a mucolytic and hydrating agent that increases airway surface liquid, reduces mucus viscosity, and promotes clearance of secretions through coughing and mucociliary transport. This mechanical action helps relieve airway obstruction and improve ventilation without pharmacological receptor targeting.
Approved indications
- Airway secretion clearance and hydration in respiratory conditions
- Symptomatic relief of cough and airway congestion
Common side effects
- Cough
- Throat irritation
- Bronchospasm (rare, in sensitive patients)
Key clinical trials
- Non-apnea Saline-contrast EIT for Lung Perfusion Imaging in Spontaneously Breathing Patients: A Prospective Cross-over Study (NA)
- Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean Section (NA)
- Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis (PHASE4)
- Effectiveness of Non-surgical Management in Rotator Cuff Calcific Tendinopathy (THE EFFECT TRIAL) (NA)
- The Efficacy of Lavender and Chamomile Essential Oils Inhalation in Management of Dental Anxiety and Pain in Children Undergoing Local Anesthesia Administration and Primary Tooth Extraction (NA)
- Alginate Dressings Versus Gauge Dressings After Pilonidal Cyst Resection: Examination of the Quality of Life (NA)
- Evaluation of the Safety of CD24-Exosomes in Patients With COVID-19 Infection (PHASE1)
- Tobramycin in Bronchiectasis Colonized With Pseudmonas Aeruginosa (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Natural saline inhalation CI brief — competitive landscape report
- Natural saline inhalation updates RSS · CI watch RSS
- Shanghai Pulmonary Hospital, Shanghai, China portfolio CI