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nano-hydroxyapatite varnish
nano-hydroxyapatite varnish is a Remineralizing agent Small molecule drug developed by Nisreen Ibrahim khan. It is currently FDA-approved for Dental caries prevention, Enamel remineralization, Dentin hypersensitivity. Also known as: (n-HAP).
Nano-hydroxyapatite varnish remineralizes and strengthens tooth enamel by depositing biocompatible calcium phosphate crystals on the tooth surface.
Nano-hydroxyapatite varnish is a small molecule intervention used in dental treatments, specifically studied for its cariostatic and remineralizing effects. It has been investigated as a potential treatment for dental caries, white spot lesions, and resistance in children, among other conditions.
At a glance
| Generic name | nano-hydroxyapatite varnish |
|---|---|
| Also known as | (n-HAP) |
| Sponsor | Nisreen Ibrahim khan |
| Drug class | Remineralizing agent |
| Target | Tooth enamel (hydroxyapatite crystal structure) |
| Modality | Small molecule |
| Therapeutic area | Dentistry / Oral Health |
| Phase | FDA-approved |
Mechanism of action
Nano-hydroxyapatite is a nanocrystalline form of the primary mineral component of tooth enamel. When applied as a varnish, it penetrates micro-defects and lesions in enamel, filling gaps and promoting remineralization. This process restores enamel integrity, reduces sensitivity, and increases resistance to acid erosion and caries.
Approved indications
- Dental caries prevention
- Enamel remineralization
- Dentin hypersensitivity
- Enamel erosion
Common side effects
- Tooth staining or discoloration
- Temporary sensitivity
- Mild gingival irritation
Key clinical trials
- Comparative Effectiveness of Remineralization Agents on Attachment-Associated Demineralization in Clear Aligner Patients (NA)
- Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents (NA)
- Cariostatic and Remineralizing Effects of Three Different Dental Varnishes (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- nano-hydroxyapatite varnish CI brief — competitive landscape report
- nano-hydroxyapatite varnish updates RSS · CI watch RSS
- Nisreen Ibrahim khan portfolio CI
Frequently asked questions about nano-hydroxyapatite varnish
What is nano-hydroxyapatite varnish?
How does nano-hydroxyapatite varnish work?
What is nano-hydroxyapatite varnish used for?
Who makes nano-hydroxyapatite varnish?
Is nano-hydroxyapatite varnish also known as anything else?
What drug class is nano-hydroxyapatite varnish in?
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What does nano-hydroxyapatite varnish target?
Related
- Drug class: All Remineralizing agent drugs
- Target: All drugs targeting Tooth enamel (hydroxyapatite crystal structure)
- Manufacturer: Nisreen Ibrahim khan — full pipeline
- Therapeutic area: All drugs in Dentistry / Oral Health
- Indication: Drugs for Dental caries prevention
- Indication: Drugs for Enamel remineralization
- Indication: Drugs for Dentin hypersensitivity
- Also known as: (n-HAP)
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing