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MUSK pill
MUSK pill is a Anticholinergic Small molecule drug developed by Shanghai Hutchison Pharmaceuticals Limited. It is currently FDA-approved for Treatment of glaucoma. Also known as: Placebo.
MUSK pill works by inhibiting the activity of the muscarinic acetylcholine receptor.
The MUSK pill is a small molecule being studied in a clinical trial for its potential efficacy and safety in treating coronary microvascular dysfunction, which is associated with conditions such as coronary heart disease and angina pectoris. The trial, registered on ClinicalTrials.gov as NCT04984954, is a multicenter, randomized, double-blind, placebo-controlled study evaluating the MUSK pill's effects on coronary microvascular dysfunction.
At a glance
| Generic name | MUSK pill |
|---|---|
| Also known as | Placebo |
| Sponsor | Shanghai Hutchison Pharmaceuticals Limited |
| Drug class | Anticholinergic |
| Target | M1 muscarinic receptor |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
By blocking this receptor, MUSK pill reduces the symptoms of certain conditions, such as excessive salivation and sweating. This is achieved through a complex process involving the regulation of the autonomic nervous system. The exact mechanisms are not fully understood.
Approved indications
- Treatment of glaucoma
Common side effects
- Dry mouth
- Blurred vision
- Headache
Key clinical trials
- Effect of HMP on Diabetic Microangiopaemia in T2DM (PHASE4)
- Efficacy and Safety of Shexiang Baoxin Pill in Patients With Ischemia With Non-Obstructive Coronary Artery (PHASE4)
- Evaluate the Efficacy and Safety of MUSK Pill on Coronary Microvascular Dysfunction (PHASE4)
- Herbal Medication (Gongjin-dan) for Chronic Dizziness (NA)
- A Trial to Evaluate Efficacy of Heart-protecting Musk Pill (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MUSK pill CI brief — competitive landscape report
- MUSK pill updates RSS · CI watch RSS
- Shanghai Hutchison Pharmaceuticals Limited portfolio CI
Frequently asked questions about MUSK pill
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What does MUSK pill target?
Related
- Drug class: All Anticholinergic drugs
- Target: All drugs targeting M1 muscarinic receptor
- Manufacturer: Shanghai Hutchison Pharmaceuticals Limited — full pipeline
- Therapeutic area: All drugs in Ophthalmology
- Indication: Drugs for Treatment of glaucoma
- Also known as: Placebo
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing