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MTA pulp dressing material
MTA (Mineral Trioxide Aggregate) pulp dressing material promotes biocompatibility and hard tissue formation through alkaline pH and calcium ion release at the dentin-pulp interface.
MTA (Mineral Trioxide Aggregate) pulp dressing material promotes biocompatibility and hard tissue formation through alkaline pH and calcium ion release at the dentin-pulp interface. Used for Direct and indirect pulp capping, Apexification in immature teeth, Root perforation repair.
At a glance
| Generic name | MTA pulp dressing material |
|---|---|
| Sponsor | Nourhan M.Aly |
| Drug class | Dental restorative material / Endodontic cement |
| Modality | Small molecule |
| Therapeutic area | Dentistry / Endodontics |
| Phase | FDA-approved |
Mechanism of action
MTA is a cement-based endodontic material that sets in the presence of moisture and releases calcium hydroxide, creating an alkaline environment that stimulates odontoblast activity and promotes remineralization. It forms a tight seal and exhibits antimicrobial properties, making it suitable for pulp capping, apexification, and root perforation repair in dental applications.
Approved indications
- Direct and indirect pulp capping
- Apexification in immature teeth
- Root perforation repair
- Retrograde filling in endodontic surgery
Common side effects
- Discoloration of tooth structure
- Difficulty in removal if needed
- Potential cytotoxicity if not properly set
Key clinical trials
- Assessment of the Number of Missing Tooth Surfaces and the Molecular Findings on the Outcomes of Vital Pulp Therapy Using Two Calcium Silicate Materials (PHASE3)
- COMPARISON of MINERAL TRIOXIDE AGGREGATE and CALCIUM HYDROXIDE AS INDIRECT PULP CAPPING AGENTS in PRIMARY MOLARS (PHASE4)
- Clinical and Radiographic Evaluation of Vital Pulpotomy Techniques in Primary Molars Using of Premixed Bioactive Bioceramic MTA (Neo-putty) as a Novel Pulpotomy Medication Versus Formocresol (NA)
- Clinical and Radiographic Evaluation of Propolis As a Hemostatic Agent for Pulpotomy of Mature Permanent Molars with Irreversible Pulpitis Using Two Different Dressing Materials (PHASE2)
- Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study (NA)
- Outcome of Full Pulpotomy Using Calcium Silicate Based Materials (NA)
- Bioactive Materials in Pulp Therapy of Primary Teeth (PHASE4)
- Evaluation of Premixed Verses Powder/Liquid Bioceramic MTA in Indirect Pulp Capping. (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MTA pulp dressing material CI brief — competitive landscape report
- MTA pulp dressing material updates RSS · CI watch RSS
- Nourhan M.Aly portfolio CI