Last reviewed 2026-04-23 · How we verify

MOVIPREP, 2-Day Split-Dosing

MOVIPREP is an osmotic laxative bowel preparation that draws water into the colon to cleanse it before medical procedures.

MOVIPREP is an osmotic laxative bowel preparation that draws water into the colon to cleanse it before medical procedures. Used for Bowel cleansing prior to colonoscopy, Bowel cleansing prior to other gastrointestinal procedures.

At a glance

Mechanism of action

MOVIPREP contains polyethylene glycol (PEG) 3350, an osmotically active agent that retains water in the intestinal lumen, combined with electrolytes (sodium chloride, potassium chloride, sodium bicarbonate, sodium sulfate) to maintain electrolyte balance. The 2-day split-dosing regimen administers the solution in two divided doses to improve tolerability and patient compliance compared to single-day dosing.

Approved indications

• Bowel cleansing prior to colonoscopy
• Bowel cleansing prior to other gastrointestinal procedures

Common side effects

• Nausea
• Vomiting
• Abdominal pain or cramping
• Bloating
• Headache

Key clinical trials

• Colon Cleansing Efficacy With 1L vs. 2L vs. 4L-PEG for Colonoscopy Among Inpatients (PHASE4)
• Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus MOVIPREP® Using 2-Day Split-Dosing and 1-Day Morning Split-Dosing Regimen in Adults. (PHASE3)

Primary sources

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Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• MOVIPREP, 2-Day Split-Dosing CI brief — competitive landscape report
• MOVIPREP, 2-Day Split-Dosing updates RSS · CI watch RSS
• Norgine portfolio CI